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The Effects of Dezocine Pretreatment on Dexamethasone Induced Perineal Irritation

Adverse Effect Clinical Trial

Official title:
The Effects of Dezocine Pretreatment on Dexamethasone Induced Perineal Irritation

Clinical Trial Summary

The purpose of this study is to investigate the efficacy of dezocine pretreatment on dexamethasone 21-phosphate induced perineal irritation (include pian and pruritus).

Clinical Trial Description

Dexamethasone is a synthetic glucocorticoid, which may cause perineal irritation when given intravenously. The major clinical manifestations are pruritus and pain，and the incidence vary between 38%-71%. Some patients undergo spontaneous remission, while others develop into severe pain or pruritus. Dezocine, a new synthetic opiate agonist-antagonist, has been used for the treatment of pain and pruritus, but its role in relieving dexamethasone induced perineal irritation has not been studied yet. The aim of this study was to investigate the efficacy of dezocine pretreatment on dexamethasone induced perineal irritation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02768168
Study type Interventional
Source General Hospital of Ningxia Medical University
Contact
Status Completed
Phase N/A
Start date May 2016
Completion date July 2016
View Details
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