Adverse Effect Clinical Trial
— WEB-ITOfficial title:
Efficacy and Safety of Weight-Based Insulin Titration (WEB-IT) Regimen Compared With Glucose Level-based Regimen in Hospitalized Patients With Type 2 Diabetes: A Randomized Controlled Study
The investigators propose to use a weight-based regimen consisting of basal-bolus insulin and preprandial rapid-acting insulin and to test its efficacy and safety in controlling blood glucose in hospitalized patients with type 2 diabetes.
Status | Recruiting |
Enrollment | 500 |
Est. completion date | February 2019 |
Est. primary completion date | December 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility |
Inclusion Criteria: - Patients aged 18 to 80 years with type 2 diabetes admitted to Endocrinology wards. Exclusion Criteria: - Patients with hepatic or renal dysfunction, cancer, or diabetic ketoacidosis; - Patients who are pregnant or lactating. |
Country | Name | City | State |
---|---|---|---|
China | the Second Affiliated Hospital of Guangzhou Medical University | Guangzhou | Guangdong |
Lead Sponsor | Collaborator |
---|---|
Second Affiliated Hospital of Guangzhou Medical University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Adverse effects | Other adverse effects except hypoglycemia | at discharge, an average of 9 days | |
Primary | Duration | Duration to achieve BG targets, including three pre-meal BG and bedtime BG | at discharge, an average of 9 days | |
Primary | Doses | Doses of insulin glargine and insulin aspart when the BG targets are achieved | at discharge, an average of 9 days | |
Secondary | Hypoglycemia | Incidence of hypoglycemia | at discharge, an average of 9 days |
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