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Clinical Trial Summary

This is a single-arm and open-label study of ATG-008 for the Treatment of Patients With advanced Solid Tumors harboring NFE 2L2, STK11, RICTOR or other specific genetic alterationts


Clinical Trial Description

This is a single-arm and open-label study. Approximately 10-12 patients will be enrolled per each genetic alterration group in the study. ATG-008 is the monotherapy for advanced solid tumors with 30mg QD. The clinical efficacy, safety and tolerability of ATG-008 will be evaluated. Addtionalal dose levels may apply after the efficacy/safety and tolerabitly of 30mg QD has been accessed by Sponosor and study steering committee. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04518137
Study type Interventional
Source Antengene Corporation
Contact
Status Terminated
Phase Phase 2
Start date April 9, 2021
Completion date May 30, 2022

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