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Clinical Trial Summary

This is an open-label, Phase I, dose-escalation study to determine the recommended Phase 2 dose (RPTD), maximum tolerated dose (MTD), and evaluate the safety and pharmacokinetic (PK) profile of budigalimab. This study will also evaluate the safety and tolerability of budigalimab in combination with Rovalpituzumab Tesirine and budigalimab in combination with venetoclax. The study will consist of 3 parts: budigalimab monotherapy dose escalation and expansion, budigalimab in combination with Rovalpituzumab Tesirine and budigalimab in combination with venetoclax.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03000257
Study type Interventional
Source AbbVie
Contact
Status Active, not recruiting
Phase Phase 1
Start date December 14, 2016
Completion date May 5, 2022

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