Advanced Malignant Tumor Clinical Trial
Official title:
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) of HRS2398 in Subjects With Advanced Malignant Tumors
The study is being conducted to determine the dose limited toxicity(DLT) and maximum tolerated dose(MTD) and recommended Phase 2 dose(RP2D) of HRS2398 in subjects with advanced malignant tumor ; The second objectives is to evaluate safety and preliminary efficacy and PK profile of HRS2398 in subjects with advanced malignant tumor ; Exploratory cohort is to explore the relationship between gene mutation and efficacy and resistance mechanisms.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT05015309 -
A Study to Investigate Safety and Tolerability of SH3765 Tablet in Patients With Advanced Malignant Tumor
|
Phase 1 | |
| Not yet recruiting |
NCT06022250 -
The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of JS207 in Patients With Advanced Malignant Tumor
|
Phase 1 | |
| Recruiting |
NCT06059508 -
Phase I Clinical Study of SHR-5495 in the Treatment of Patients With Advanced Malignant Tumors
|
Phase 1 | |
| Recruiting |
NCT05851092 -
Phase I Clinical Study of HRS-2189 in the Treatment of Patients With Advanced Malignant Tumors
|
Phase 1 | |
| Suspended |
NCT05089461 -
A Study to Evaluate the Cardiac Safety of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Malignant Tumor
|
Phase 2 | |
| Active, not recruiting |
NCT04296994 -
A Study of QL1706 in Subjects With Advanced Malignant Tumor
|
Phase 1 | |
| Recruiting |
NCT05416359 -
Phase I Clinical Trial of TQB3915 Tablets in Subjects With Advanced Malignant Solid Tumors
|
Phase 1 | |
| Recruiting |
NCT04954456 -
A Study of Bispecific Antibody QLS31901 in Patients With Advanced or Metastatic Malignancies
|
Phase 1 | |
| Recruiting |
NCT04326829 -
QL1604 Monotherapy for dMMR or MSI-H Advanced Solid Tumors
|
Phase 2 | |
| Recruiting |
NCT04739111 -
An Exploratory Clinical Study of LDP Combined With CDP1 in Patients With Advanced Malignant Tumor
|
Phase 1 | |
| Recruiting |
NCT05767060 -
BAT7104 Injection in Patients With Advanced Malignant Tumors.
|
Phase 1 | |
| Recruiting |
NCT04975204 -
A Clinical Trial of TQB3909 Tablets in Subjects With Advanced Malignant Tumors
|
Phase 1 | |
| Completed |
NCT05042908 -
Evaluation of LBL-003 Phase I Study in Patients With Advanced Malignancies
|
Phase 1 | |
| Recruiting |
NCT04412564 -
A Study of TQ-B3101 Capsules in Subjects With Advanced Malignant Tumor
|
Phase 2 | |
| Recruiting |
NCT05198505 -
Clinical Trial of TQB2868 Injection in Subjects With Advanced Malignant Tumors
|
Phase 1 | |
| Not yet recruiting |
NCT05318833 -
A Study of HRS7415 Tablets in Patients With Advanced Malignant Tumors
|
Phase 1 |