Pain Clinical Trial
Official title:
Water Method With Water Exchange Versus Air Insufflation in Patients With Incomplete Colonoscopy: a Prospective Randomized, Controlled Trial
Water method with water exchange has been shown to reduce medication requirement and pain
experienced during colonoscopy. It increases the success rate of cecal intubation in sedated
and unsedated patients undergoing screening colonoscopy. Exchange of water during scope
insertion minimizes distension of the colonic lumen and decreases loop formation. Exclusion
of air from the colon during insertion by omission of air insufflations and suction removal
of residual air prevent elongation of the colon. These maneuvers facilitate colonoscopy
insertion in average patients and may enhance the success of difficult colonoscopy.
Colonoscopy has been considered the gold standard procedure in screening for colorectal
disease. However, 5-10% of colonoscopies are incomplete due to patient discomfort, difficult
anatomy and prior abdominal or pelvic surgery. The investigators postulate that these
patients may benefit from using the water method for colonoscopy. In this proposal the
investigators test the hypothesis that compared with conventional air insufflations the
water method with water exchange significantly enhances the success rate of cecal intubation
in patients with immediately failed colonoscopy.
The aim of the study is to compare the outcome of colonoscopy using the water method versus
the conventional air method in patients with incomplete colonoscopy. The primary outcome is
cecal intubation success rate. The secondary outcomes include cecal intubation time, maximum
pain score during colonoscopy, overall pain score after colonoscopy and adenoma detection
rate.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Screening
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