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Adenoma Colon clinical trials

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NCT ID: NCT05492656 Completed - Colonic Polyp Clinical Trials

Accuracy of CADx System for White Light Colonic Polyp Characterization

GIC
Start date: August 5, 2022
Phase:
Study type: Observational

The endoscopist performances in the optical diagnosis (OD) of colonic polyps with the available technologies vary widely across centers and across endoscopists. The OD process is strictly related to the operator training and expertise. Most of the available studies in optical characterization have been carried out by expert endoscopist in tertiary high volume centers, and weren't replied on large unselected populations. For these reasons, at the moment the optical characterization of polypoid lesions can't replace, in the everyday clinical practice, the histopathological evaluation of resected polyps. Artificial intelligence (AI)-based systems have the potential to make optical characterization process of colonic polyps easier and more reliable, thus supporting the endoscopist in the application of leave-in-situ and of resect-and-discard strategies. The implementation of such strategies would lead to a significant economic saving and a decrease of risks and complications related to unnecessary polypectomy. GI-Genius System (Medtronic Inc, Minneaopolis, USA) is a CNN-based algorithm allowing an automatic OD of colonic polyps. This system does not require dedicated light setting for polyp evaluation as it works with white light high definition images, which are the actual standard in every endoscopic unit. During colonoscopy, when a polyp is framed within the screen, a green detection box surrounds the polyp and the system automatically provides (whenever possible) the optical diagnosis labeling the polyp as "adenoma or non-adenoma". When the automatic polyp charaterization is unfeasible the label "no prediction" appears. Nowadays only few data about the feasibility and performances of this system in clinical practice are available. In addition published studies are mostly focused on technical rather thann clinical issues. The present prospective observational trial is primarily aimed at evaluating the diagnostic accuracy of optical characterization of colonic polyps <= 1 cm using GI-Genius System in daily clinical practice, having histopathology examination as reference standard.

NCT ID: NCT05423964 Recruiting - Colorectal Cancer Clinical Trials

Impact of AI on Trainee ADR

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Adenoma detection rate (ADR) is a validated quality metric for colonoscopy with higher ADR correlated with improved colorectal cancer outcomes. Artificial intelligence (AI) can automatically detect polyps on the video monitor which may allow endoscopists in training to improve their ADR. Objective and Purpose of the study: Measure the effect of AI in a prospective, randomized manner to determine its impact on ADR of Gastroenterology trainees.

NCT ID: NCT05422820 Completed - Colorectal Cancer Clinical Trials

The Argentina Brief Colonoscopy Difficulty Score (ABCD)

ABCD
Start date: July 1, 2022
Phase:
Study type: Observational [Patient Registry]

Colonoscopy completion by caecal intubation seldom represents a significant effort for the endoscopist. In this situation, additional techniques are necessary to achieve this goal: patients' manual abdominal compression, postural changes, and endoscopist relay. To date, no tool allows colonoscopy technical difficulty grading. This study pursues to describe the frequency of additional techniques for caecal intubation in a large sample of Argentinians in different centres who undergo colonoscopy for attending purposes, to develop a novel score for assessing colonoscopy technical difficulty.

NCT ID: NCT05178095 Completed - Clinical trials for Gastrointestinal Neoplasms

Artificial Intelligence in Colonic Polyp Detection

Start date: September 30, 2020
Phase: N/A
Study type: Interventional

A randomized, controlled study investigating the potential benefits of artificial intelligence (AI) in the detection of colonic polyps during outpatient colonoscopy. Randomization between the use of AI and no AI is performed before the study procedure.

NCT ID: NCT05158725 Recruiting - Adenoma Colon Clinical Trials

Comparison of Colonoscopy Adenoma Detection Yield

Start date: November 8, 2021
Phase: N/A
Study type: Interventional

A Prospective Randomized Comparison of colonoscopy Adenoma Detection Yield of (i) Standard Colonoscopy (SC), (ii) artificial intelligence (Discovery) aided colonoscopy, and (iii) artificial intelligence (Discovery) and permanently mounted balloon (G-EYE®) aided colonoscopy.

NCT ID: NCT05080088 Completed - Colorectal Cancer Clinical Trials

Retrospective Evaluation of 3 Colonic Adenoma Detection Strategies

COLODETECT
Start date: April 6, 2021
Phase:
Study type: Observational

Retrospective study, single blind (patient), allowing a posteriori clinical data collection of 90 patients during their passage to the ambulatory endoscopy circuit, to consider 3 groups and thus to deduce a colonic adenoma detection rate for each arm : - Colonoscopy Only Group - Artificial intelligence only group (IA GI GENIUS ™ alone) - Endoscopic Cap and Artificial Intelligence Group (endoscopy cap associated with the GI GENIUS ™ IA System)

NCT ID: NCT05064124 Not yet recruiting - Colorectal Polyp Clinical Trials

Early diAgnosis Real-Time Healthcare System for CANcer Trial

EARTHSCAN
Start date: June 2024
Phase:
Study type: Observational

The purpose of the study is to assess whether the AI characterisation system of the CADDIE device improves the endoscopists accuracy in the optical diagnosis of diminutive colorectal polyps in the bowel during colonoscopy. Participants will either have a colonoscopy with the assistance of the CADDIE device characterisation AI system ("intervention group") or have a colonoscopy in line with routine clinical practice i.e., without the CADDIE device characterisation AI system ("control group"). The randomisation method of this trial will allocate enrolled participants to the "intervention" group and to the "control" group by a technique similar to flipping a coin.

NCT ID: NCT04979962 Completed - Adenoma Colon Clinical Trials

AI Colorectal Polyp Detection

Start date: November 24, 2021
Phase: N/A
Study type: Interventional

This study is intended to demonstrate the superiority of colorectal polyp detection using computer-assisted colonoscopy compared to conventional colonoscopy.

NCT ID: NCT04756453 Recruiting - Adenoma Colon Clinical Trials

The Effect of Clip-traction on ESD Resection Time.

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Patients scheduled for an endoscopic submucosal dissection(ESD) in the colorectum will be randomized to the use of a traction device(consisting of an endoscopic clip with a loop of dental floss secured in the lesion to be removed, another clip will anchor the loop to adjacent bowel wall) or a standard ESD.

NCT ID: NCT04739722 Active, not recruiting - Colorectal Cancer Clinical Trials

Colorectal Cancer and Pre-Cancerous Adenoma Non-Invasive Detection Test Study

CRC-PREVENT
Start date: April 12, 2021
Phase: N/A
Study type: Interventional

This study will be a prospective analysis conducted by Geneoscopy Inc. to evaluate the Colosense test, which is a multi-target stool RNA test for colorectal screening.