Comparison of 4-weeks of Motor Relearning Program and Mirror Therapy in Improving Upper Limb Motor Function in Stroke Patients.

Acute Stroke Clinical Trial

Official title:

Comparison of 4-weeks of Motor Relearning Program and Mirror Therapy in Improving Upper Limb Motor Function in Stroke Patients.

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT06074081
• Other study ID #: Motor Relearning Program
• Status: Enrolling by invitation
• Phase: N/A
• Start date: September 4, 2023
• Est. completion date: February 27, 2024

Study information

• Verified date: October 2023
• Source: Yusra Medical and Dental College
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Cerebrovascular accident(CVA) or stroke is one of common condition affecting people in developed and underdeveloped countries. MRP is a therapy to regain particular motor function and neglecting accessory movements by engaging cognitive behavior. Mirror therapy enhance functional activities in patient with hemiplegic stroke. For betterment of result high quality methodological studies and larger sample size is required.

Description:

Cerebrovascular accident(CVA) or stroke is one of common condition affecting people in developed and underdeveloped countries. Mostly patient with stroke face many disabilities and the most important one is upper limb motor impairment. For the optimization of upper extremity and prevention of patient from permanent disability it is essential to promotes Neuro-rehabilitation interventions. Physiotherapy techniques need to be monotonous, thorough and task oriented for neuroplasticity to generate better recovery. There is notable enhancement in ADLS when the rehabilitation program starts within 16 hours to 6 months after stroke In improving upper extremity motor functions there are tremendous types of techniques used i.e. Proprioceptive neuromuscular facilitation(PNF),Brunnstorm, Bobath therapy, Motor relearning program(MRP),Constraint induced movement therapy(CIMT) and Mirror therapy(MT).Out of which we are using two basic techniques i.e. motor relearning program(MRP) and mirror therapy(MT).Mirror therapy enhance functional activities in patient with hemiplegic stroke. For betterment of result high quality methodological studies and larger sample size is required. Mirror therapy enhance functional activities in patient with hemiplegic stroke. MRP is a therapy to regain particular motor function and neglecting accessory movements by engaging cognitive behavior .MRP is a therapy to regain particular motor function and neglecting accessory movements by engaging cognitive behavior.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 28
• Est. completion date: February 27, 2024
• Est. primary completion date: December 26, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria

• Acute(hemiplegic attack within 1-2 weeks) and sub-acute stroke(hemiplegic attack within 3- 11 weeks).
• 20 to 80 years.
• No physical deformity prior to stroke
• No history of serious underlying pathology and structural deformities.

Exclusion Criteria:

• Patient with chronic hemiplegic stroke.
• Patient with congenital deformity.

Related Conditions & MeSH terms

• Acute Stroke
• Stroke

Intervention

Other:
• motor relearning program
MRP is a therapy to regain particular motor function and neglecting accessory movements by engaging cognitive behavior .
• mirror therapy
Mirror therapy enhance functional activities in patient with hemiplegic stroke. For betterment of result high quality methodological studies and larger sample size is required.

Locations

Country	Name	City	State
Pakistan	Maham Nasir	Islamabad	Federal

Sponsors (1)

Lead Sponsor	Collaborator
Yusra Medical and Dental College

Country where clinical trial is conducted

Pakistan, 

References & Publications (16)

Arfianti L, Rochman F, Hidayati HB, Subadi I. The addition of mirror therapy

Fagundes NCF, Almeida APCPSC, Vilhena KFB, Magno MB, Maia LC, Lima RR. Periodontitis As A Risk Factor For Stroke: A Systematic Review And Meta-Analysis. Vasc Health Risk Manag. 2019 Nov 6;15:519-532. doi: 10.2147/VHRM.S204097. eCollection 2019. — View Citation

Gandhi DB, Sterba A, Khatter H, Pandian JD. Mirror Therapy in Stroke Rehabilitation: Current Perspectives. Ther Clin Risk Manag. 2020 Feb 7;16:75-85. doi: 10.2147/TCRM.S206883. eCollection 2020. — View Citation

Hassani Z, Mokhtarinia HR, Kahlaee AH, Gabel CP. Translation, Validity, and Reliability of the Upper Extremity Fugl-Meyer Assessment (FMA-UE) in Persian Speaking Stroke Patients. Iranian Rehabilitation Journal. 2022 Mar 10;20:37-46.

Hsieh YW, Lin YH, Zhu JD, Wu CY, Lin YP, Chen CC. Treatment Effects of Upper Limb Action Observation Therapy and Mirror Therapy on Rehabilitation Outcomes after Subacute Stroke: A Pilot Study. Behav Neurol. 2020 Jan 2;2020:6250524. doi: 10.1155/2020/6250524. eCollection 2020. — View Citation

improved upper limb motor recovery and level of independence after stroke: a randomized controlled trial. CadernosBrasileiros de TerapiaOcupacional. 2022 Sep 2;30.

Jan S, Arsh A, Darain H, Gul S. A randomized control trial comparing the effects of motor relearning programme and mirror therapy for improving upper limb motor functions in stroke patients. J Pak Med Assoc. 2019 Sep;69(9):1242-1245. — View Citation

Malouin F, Pichard L, Bonneau C, Durand A, Corriveau D. Evaluating motor recovery early after stroke: comparison of the Fugl-Meyer Assessment and the Motor Assessment Scale. Arch Phys Med Rehabil. 1994 Nov;75(11):1206-12. doi: 10.1016/0003-9993(94)90006-x. — View Citation

Maratis J, Wahidin A, Ivanali K. COMPARE THE EFFECTIVENESS OF CONSTRAINT INDUCED MOVEMENT THERAPY AND MOTOR RELEARNING PROGRAMME IN POST STROKE PATIENTS. In Academic Physiotherapy Conference Proceeding 2021 (pp. 179-190).

Murphy SJ, Werring DJ. Stroke: causes and clinical features. Medicine (Abingdon). 2020 Sep;48(9):561-566. doi: 10.1016/j.mpmed.2020.06.002. Epub 2020 Aug 6. — View Citation

Ng JC, Churojana A, Pongpech S, Vu LD, Sadikin C, Mahadevan J, Subramaniam J, Jocson VE, Lee W. Current state of acute stroke care in Southeast Asian countries. Interv Neuroradiol. 2019 Jun;25(3):291-296. doi: 10.1177/1591019918811804. Epub 2018 Nov 21. — View Citation

Platz T, Pinkowski C, van Wijck F, Kim IH, di Bella P, Johnson G. Reliability and validity of arm function assessment with standardized guidelines for the Fugl-Meyer Test, Action Research Arm Test and Box and Block Test: a multicentre study. Clin Rehabil. 2005 Jun;19(4):404-11. doi: 10.1191/0269215505cr832oa. — View Citation

Rehme AK, Eickhoff SB, Rottschy C, Fink GR, Grefkes C. Activation likelihood estimation meta-analysis of motor-related neural activity after stroke. Neuroimage. 2012 Feb 1;59(3):2771-82. doi: 10.1016/j.neuroimage.2011.10.023. Epub 2011 Oct 17. — View Citation

Ullah I, Arsh A, Zahir A, Jan S. Motor relearning program along with electrical stimulation for improving upper limb function in stroke patients: A quasi experimental study. Pak J Med Sci. 2020 Nov-Dec;36(7):1613-1617. doi: 10.12669/pjms.36.7.2351. — View Citation

Zeng W, Guo Y, Wu G, Liu X, Fang Q. Mirror therapy for motor function of the upper extremity in patients with stroke: A meta-analysis. J Rehabil Med. 2018 Jan 10;50(1):8-15. doi: 10.2340/16501977-2287. — View Citation

Zhang Y, Xing Y, Li C, Hua Y, Hu J, Wang Y, Ya R, Meng Q, Bai Y. Mirror therapy for unilateral neglect after stroke: A systematic review. Eur J Neurol. 2022 Jan;29(1):358-371. doi: 10.1111/ene.15122. Epub 2021 Oct 5. — View Citation

* Note: There are 16 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	fugl meyer assessment scale (FMA)	This test is recommended for checking functional return of patient having impairments with stroke.Test consists on the base of assessing patient with moving limb in low tone movements or synergistic pattern and then move actively back to normal function. Total scoring for upper limb is 18.	upto 4 weeks