Effect of Sour Liquid On Swallowing Function of the Patients With Stroke

Acute Stroke Clinical Trial

Official title:

Effect of Sour Liquid On Swallowing Function of the Patients With Post-Stroke Dysphagia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06013254
• Other study ID #: TÜTF-BAEK 2021/214
• Status: Completed
• Phase: N/A
• Start date: July 15, 2021
• Est. completion date: November 20, 2022

Study information

• Verified date: August 2023
• Source: Trakya University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study was to evaluate the effect of early administration of sour liquid on swallowing function of patients with post-stroke dysphagia. Hypothesis of the study were; H0: The sour liquid given early to patients with post-stroke dysphagia does not have an effect on swallowing function H1: The sour liquid given early to patients with post-stroke dysphagia has an effect on swallowing function The data of the study were collected using the "Personal Information Form," "Standard Swallowing Test," "Gagging Swallowing Screening Test (GUSS)," and the " National Institute of Health Stroke Scale (NIHSS)". Early administration of sour liquid to patients with post-stroke dysphagia was found to have a positive effect on swallowing function.

Description:

Background: Untreated and undetected swallowing disorders lead to increased morbidity and mortality in acute stroke patients due to inadequate nutrition, dehydration, and aspiration pneumonia leading to prolonged hospital stays, decreased functionality, and increased long-term care needs. The aim of this study was to evaluate the effect of early administration of sour liquid on swallowing function of patients with post-stroke dysphagia. Materials and methods: This study was a randomized controlled trial, which was conducted with 95 patients with confirmed diagnosis of ischemic stroke and dysphagia, admitted to the neurology department of a university hospital. The intervention group (n=47) received 4 ml of room temperature lemon juice, while the control group (n=48) received 4 ml of room temperature water before breakfast, lunch, and dinner for a duration of 7 days. The Standard Swallowing Test, Gagging Swallowing Screen, and National Institutes of Health Stroke Scale were applied. Swallowing function and stroke severity were assessed at initial assessment, at the end of the 7th and 30th days.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 95
• Est. completion date: November 20, 2022
• Est. primary completion date: July 15, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• diagnosed with ischemic stroke,
• had not completed the first 72 hours after diagnosis,
• developed swallowing disorders,
• volunteered to participate in the study

Exclusion Criteria:

• diagnosed hemorrhagic stroke,
• had completed the first 72 hours after diagnosis,
• not developed swallowing disorders,
• not volunteered to participate in the study

Related Conditions & MeSH terms

• Acute Stroke
• Stroke

Intervention

Dietary Supplement:
• sour liquid
applying lemon juice

Locations

Country	Name	City	State
Turkey	Trakya University Faculty of Medicine	Edirne

Sponsors (1)

Lead Sponsor	Collaborator
Trakya University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	swallowing assessments using the Gugging Swallowing Screen (GUSS) score	improve the swallowing disorders of patients who have experienced acute stroke through the administration of sour taste. patients in both the intervention and control groups underwent advanced swallowing assessments using the GUSS.; Gugging Swallowing Screen (GUSS)consists of two parts including an indirect swallowing test with three subtests, and a direct swallowing test with four subtests. Evaluation is made on a scale of 0-20 as follows: 0-9 points indicate severe swallowing disorder with high risk of aspiration, 10-14 points indicate moderate swallowing disorder with moderate risk of aspiration, 15-19 points indicate mild swallowing disorder with low risk of aspiration, and 20 points indicate no swallowing disorder.	initial assessment, 7th day assessment, 30th day assessment