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Comparing Formulations of Mechanical Power Using Geometric Methods

Acute Respiratory Distress Syndrome Clinical Trial

Official title:
Comparing Formulations of Mechanical Power Using Geometric Methods at Different Inspiratory Rise and Pause Times: A Validation Study

Clinical Trial Summary

We aimed to compare different formulations of mechanical power using geometric methods at varying inspiratory rise and pause times.

Clinical Trial Description

One of the formulas used to calculate mechanical power (MP) is the dynamic mechanical power formula (MPdyn) developed by Asar et al. This formula, in Volume-Controlled Ventilation (VCV) mode, calculates the same MP values as the comprehensive mechanical power formula (MPrs) from Gattinoni et al., without requiring the inspiratory resistance value. Similarly, in Pressure-Controlled Ventilation (PCV) mode, the MPdyn formula calculates mechanical power values comparable to those from the mechanical power formula (MPlm) proposed by Trinkle et al., also without the need for inspiratory resistance. However, the MPdyn formula has not been compared with the geometric method, considered the gold standard for mechanical power calculation. This limitation has been highlighted as a drawback for clinical use, particularly when applying the formula in both VCV and PCV modes. In this study, we aim to compare the MPdyn formula with the MPLM and MPrs formulas, against the standard geometric method (MPstd), for mechanical power calculations in ARDS patients during both pressure-controlled and volume-controlled ventilation, at varying inspiratory rise (Tslope) and pause times (Tpause). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06413472
Study type Observational
Source Basaksehir Çam & Sakura City Hospital
Contact
Status Active, not recruiting
Phase
Start date January 1, 2024
Completion date June 1, 2024
View Details
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