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Acute Phase Reaction clinical trials

View clinical trials related to Acute Phase Reaction.

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NCT ID: NCT06284395 Recruiting - Survivorship Clinical Trials

Two Schemes Response in Multiple Myeloma

Start date: November 20, 2023
Phase:
Study type: Observational

Retrospective study based on medical records of patients with multiple myeloma, eligible for stem cell transplantation, who received, first-line, the VTD or TD combination.

NCT ID: NCT05926089 Completed - Pneumonia Clinical Trials

Acute Phase Reactant in Non-COVID-19 Bacterial Pneumonia

Start date: October 1, 2020
Phase:
Study type: Observational

This study is a cross-sectional study, was conducted at Chest department of Kasr Al-ainy Hospital, Cairo university during the period between October 2020 and April 2021. The aim of the work was to evaluate levels of acute phase reactants(APR) in Non-COVID-19 bacterial pneumonia, and to correlate between levels of APR and the disease severity.

NCT ID: NCT05889312 Not yet recruiting - Cancer Clinical Trials

Assessing Cancer Treatment Response to Therapy Using 18F-FSPG PET

Start date: September 2023
Phase:
Study type: Observational

Prospective single centre non-randomised exploratory observational study to measure changes in tumour cellular redox status with 18F-FSPG PET in stage 3 non-small cell lung cancer (NSCLC) and stage 3 and 4 head and neck squamous cell cancer (HNSCC) at baseline and during standard of care treatment, and to compare this with 18F-FDG PET/CT and RECIST 1.1 response at 12 weeks.

NCT ID: NCT05656339 Recruiting - Insulin Resistance Clinical Trials

Metabolic Effects of Whey Protein Supplementation After Fasting in Volunteers

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

This study aims to investigate the early metabolic effects and acute phase response of an oral clear supplement containing whey protein plus carbohydrates in young healthy volunteers during fasting-induced organic response

NCT ID: NCT05642117 Completed - Emergencies Clinical Trials

Pediatric Telephone Center Board 15

CTPC15
Start date: May 1, 2021
Phase:
Study type: Observational

This study evaluates the follow-up of advices given in a Urgent Medical Aid Service (SAMU 29) for every pediatric's emergency call under 15yo and try to evaluate the adhesion's factors.

NCT ID: NCT04838938 Completed - Treatment Clinical Trials

Personalized Medicine in Patients With Infective Endocarditis

Start date: March 1, 2021
Phase:
Study type: Observational [Patient Registry]

The hypothesis underlying this work is the identification of different sub phenotypes of patients with infective endocarditis through the study of the host's response to infection. Furthemore, metagenomic sequencing may be a helpful supplement to IE diagnostic, especially when conventional tests fail to yield a diagnosis.

NCT ID: NCT04719481 Not yet recruiting - Clinical trials for Postmenopausal Osteoporosis

Pravastatin Reduces Acute Phase Response of Zoledronic Acid

Start date: November 2021
Phase: Phase 4
Study type: Interventional

Acute phase response (APR) is one of the most common adverse events in osteoporosis with zoledronic acid treatment. It's reported that this reaction is related to the blockade of the mevalonate pathway, leading to isopentenyl pyrophosphate (IPP) accumulation. And the latter can active γδT cells in the circulation, resulting in inflammatory cytokine release. Statins can inhibit the conversion of HMG-CoA to mevalonate that may reduce the accumulation of IPP. Therefore, it is possible that statins can be taken in advance to reduce APR caused by zoledronic acid infusion.

NCT ID: NCT04383561 Completed - Inflammation Clinical Trials

Relationship Between LRG and Periodontal Disease

Start date: September 30, 2019
Phase: N/A
Study type: Interventional

This study aimed to investigate gingival crevicular fluid (GCF) and serum levels of LRG, interleukin (IL)-6 and tumor necrosis factor (TNF)-α in patients with periodontitis before and after non-surgical periodontal treatment.

NCT ID: NCT03741023 Enrolling by invitation - Clinical trials for Acute Phase Response

Disorders of the Acute Phase Response Following Trauma and Invasive Surgery

Start date: December 12, 2019
Phase: N/A
Study type: Interventional

The purpose of the proposed study is to test these hypotheses through the following aims: 1. To determine if early plasmin activation following severe injury correlates with SIRS, TIC and complications throughout convalescence in both trauma and surgical patients. 2. To determine if early plasmin activation following severe injury correlates with plasminogen consumption and poor plasmin activity later in convalescence.

NCT ID: NCT03398304 Enrolling by invitation - Clinical trials for Acute Phase Response

Defining the Temporal Changes in the Acute Phase Response During Graded Exercise: A Prospective Study

Start date: November 29, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to detail the precise temporal changes in the APR that occur in response to exercise in order to determine the types of exercise that confer maximal reparative fibrinolysis. Published research and preliminary studies conducted in our lab suggest that different types of exercise will preferentially activate fibrinolysis over coagulation, thereby promoting improved global tissue health [8]. As such, measuring markers of the APR in healthy individuals 1) at rest, 2) walking (light intensity exercise), 3) running (moderate intensity exercise), and 4) following endurance running (a marathon) will allow us to establish a baseline for the temporal changes in the APR that avoid activation of the procoagulant survival phase while maximizing the repair phase. Specific aims 1. To measure the acute phase response fibrinolysis, plasminogen consumption, and inflammatory profiles of healthy individuals before and after graded exercise (at rest, light intensity, medium intensity) and after prolonged exercise at medium intensity as defined by changes in fibrinolysis, plasminogen consumption, and inflammatory response. 2. To track the APR through modulated exercise in order to determine the type of exercise that enhances physiologic benefit and limits harm.