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Acute Pericarditis clinical trials

View clinical trials related to Acute Pericarditis.

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NCT ID: NCT06293924 Not yet recruiting - Clinical trials for Pericardial Effusion

Pericardial Fluid Analysis in Recurrent Pericarditis

PEFLANA
Start date: March 2024
Phase:
Study type: Observational [Patient Registry]

This clinical trial aims to examine the biochemical and cytological features of pericardial effusion during acute and recurrent pericarditis and to understand the molecular factors responsible for pathogenesis. The primary objective of this study is to identify and validate diagnostic criteria in pericardial fluid analysis that can differentiate patients with acute and recurrent pericarditis from those with only pericardial fluid but no inflammation. This study will enroll patients with acute pericarditis who require pericardiocentesis for either diagnostic or therapeutic purposes. Two control groups will also be included: one consisting of patients who need cardiac surgery with a collection of pericardial fluid, and the other consisting of patients who require pericardiocentesis for non-inflammatory pericardial effusion. The purpose of the study is to compare the cell activation status and cytokines present in pericardial fluid during acute pericarditis with those present during other pericardial pathologies.

NCT ID: NCT03224585 Terminated - Acute Pericarditis Clinical Trials

Treatment of Acute Pericarditis With Anakinra

Start date: May 11, 2018
Phase: Phase 2
Study type: Interventional

The goal of this study is to determine the safety and efficacy of anakinra for the treatment of acute pericarditis when initiated within 6 hours of diagnosis and continued for 3 or 7 days. 1. to determine the efficacy of anakinra with respect to chest pain resolution 2. to determine the safety of anakinra with respect to adverse drug events