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Acute Pain clinical trials

View clinical trials related to Acute Pain.

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NCT ID: NCT02662764 Completed - Clinical trials for Moderate-to-severe Acute Pain

Study to Evaluate the Overall Performance of the Zalviso Systemâ„¢ (Sufentanil Sublingual Tablet System) 15 mcg

Start date: September 28, 2016
Phase: Phase 3
Study type: Interventional

Study to evaluate the overall performance of the Zalviso Systemâ„¢ (sufentanil sublingual tablet system) 15 mcg

NCT ID: NCT02656875 Completed - Acute Pain Clinical Trials

A Open-label Study to Evaluate the Safety of TRV130 in Patients With Acute Pain

ATHENA-1
Start date: December 2015
Phase: Phase 3
Study type: Interventional

Patients with moderate to severe pain caused by medical conditions or surgery, who require IV opioid therapy may be enrolled in this open label safety study. Patients will be treated with TRV130 by IV bolus, PCA (patient-controlled analgesia) administration, or both, as determined by the investigator, for a duration not to exceed 14 days.

NCT ID: NCT02645903 Completed - Acute Pain Clinical Trials

Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy

Start date: May 2015
Phase: Phase 4
Study type: Interventional

Living donor organ transplantation has increased in recent years due to an increased need for organs. The objective of this study was to investigate the effects of a TAP block on postoperative analgesia and opioid consumption in liver transplantation donors in whom a right lateral extending upper mid-line abdominal incision was used.

NCT ID: NCT02640053 Completed - Breast Carcinoma Clinical Trials

Topical Cryotherapy in Reducing Pain in Patients With Chemotherapy Induced Peripheral Neuropathy or Paclitaxel Induced Acute Pain Syndrome

Start date: December 23, 2015
Phase: N/A
Study type: Interventional

This randomized pilot clinical trial studies topical cryotherapy (cooling hands and feet with ice bags) in reducing pain in patients with chemotherapy induced peripheral neuropathy or paclitaxel induced acute pain syndrome. Peripheral neuropathy is a nerve problem that causes pain, numbness, tingling, swelling, or muscle weakness in different parts of the body. Paclitaxel produces a disabling syndrome of acute aches and pains. Topical cryotherapy is being studied to see if it can help relieve pain from peripheral neuropathy or acute pain syndrome caused by chemotherapy.

NCT ID: NCT02621619 Completed - Acute Pain Clinical Trials

IV Acetaminophen as an Analgesic Adjunct

Start date: March 2016
Phase: Phase 4
Study type: Interventional

To determine the efficacy of intravenous (IV) acetaminophen as an analgesic adjunct to IV hydromorphone in the treatment of acute severe pain in the elderly Emergency Department (ED) patients.

NCT ID: NCT02605343 Completed - Surgery Clinical Trials

Prospective Observational Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Patients Undergoing Elective Surgical Procedures

Start date: August 2015
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the effect of pharmacogenetics (PGx) guided treatment when implemented into the pre-operative process for patients undergoing bowel surgery, major urologic procedure, or major ventral hernia repair and requiring post-operative acute pain management in an inpatient basis, as compared to a group of subjects with the same attributes without the guidance of PGx testing (historical control group). This study will also evaluate the frequency with which the standard analgesic care plan is adjusted by test results.

NCT ID: NCT02602483 Completed - Clinical trials for Temporomandibular Joint Disorders

Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD).

Start date: December 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The objetive of this study is to explore the efficacy and safety of a triple combination of ibuprofen, magnesium and ascorbic acid for acute pain treatment in TMJD patients

NCT ID: NCT02590029 Completed - Acute Pain Clinical Trials

Psychosocial Support for Acute Hospital Pain and Distress

Start date: November 2015
Phase: N/A
Study type: Interventional

The purpose of this randomized study is to determine the impact of three different types of psychosocial support delivered by social workers to patients reporting uncontrolled pain during a hospital stay. This study will examine the differential effects of brief mindfulness training, therapeutic suggestion, and psychoeducation for patients reporting uncontrolled pain.

NCT ID: NCT02576132 Completed - Acute Pain Clinical Trials

Pupillometry for Pain Assessment in Critically Ill Patients

Start date: November 2011
Phase: N/A
Study type: Observational

This study was part of a quality improvement project at the Department of Anesthesiology and Intensive Care Medicine, Charité - Universitaetsmedizin Berlin. Being in pain is reported to be one of the most important stressors in critically ill patients and worsens outcome. The evaluation of pain using validated scores in patients who are able to self-report significantly improves the quality of analgesic therapy and health related outcomes in intensive care patients. However, behavioral pain score that are used in sedated or delirious patients, often underestimate the severity of pain. The primary aim of this study is to investigate if measurement of the pupillary light reflex Amplitude correlates with the results of pain assessment using validated pain scores in critically ill patients.

NCT ID: NCT02565342 Completed - Acute Pain Clinical Trials

Interscalene Brachial Plexus Block to Treat Pain After Clavicular Surgery

Start date: September 2015
Phase: Phase 4
Study type: Interventional

The sensory innervation of the clavicle remains an area of debate. Regional nerve blocks aimed at relieving pre- and post-operative pain include the superficial cervical plexus blocks, interscalene blocks and a combined version of the above. In this case study, the investigators aim to describe the protocol used in a university hospital: general anaesthesia with interscalene brachial plexus block, followed by optional iv morphine administration in phase 1 recovery and oral oxycodone on the ward.