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Alpha-1 Anti-Trypsin (AAT) Treatment in Acute Myocardial Infarction — VCU-Alpha1RT  

Acute Myocardial Infarction Clinical Trial

Official title:
Alpha-1 Anti-Trypsin (AAT) to Quench the Acute Inflammatory Response in ST-segment Elevation Acute Myocardial Infarction

Clinical Trial Summary

Acute myocardial infarction is characterized by an intense inflammatory response.

The degree of the response influences clinical outcome, with 'more' inflammation promoting heart failure. In this study we plan to determine whether treatment with plasma derived alpha-1 antitrypsin will quench the inflammatory response in patients with acute ST-segment elevation myocardial infarction (STEMI).

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01936896
Study type Interventional
Source Virginia Commonwealth University
Contact
Status Completed
Phase Phase 1/Phase 2
Start date December 2013
Completion date July 2014
View Details
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