Right Ventricular Damage in Cardiovascular Magnetic Resonance

Acute Myocardial Infarction Clinical Trial

Official title:

Right Ventricular Damage in ST-Elevation Myocardial Infarction. Risk Stratification by Visualization of Wall Motion, Edema and Delayed Enhancement Cardiovascular Magnetic Resonance

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01359306
• Other study ID #: RV-Damage 1/2007
• Status: Completed
• Phase: N/A
• First received: May 20, 2011
• Last updated: May 23, 2011
• Start date: February 2006
• Est. completion date: May 2008

Study information

• Verified date: May 2011
• Source: University of Leipzig
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: Ethics Commission
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to determine the predictors of right ventricular damage (RVD) assessed by wall motion abnormalities, edema, myocardial salvage and delayed enhancement (DE)cardiac magnetic resonance imaging in acute ST-elevation myocardial infarction (STEMI) and its prognostic significance.

The investigators hypothesize that ischemia related changes of the myocardium are also visible in the right ventricle and that they have an impact on patient outcome.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 524
• Est. completion date: May 2008
• Est. primary completion date: May 2008
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Onset of symptoms <12 h before angioplasty.

• ST-segment elevation of at least 0.1 mV in =2 extremity leads or at least 0.2 mV in =2 precordial leads.

Exclusion Criteria:

• Contraindications to CMR as implanted defibrillators, pacemakers, ferromagnetic intracranial metallic implants or pulmonary metallic splints and claustrophobia. A further exclusion criterion was prior fibrinolysis.

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Acute Myocardial Infarction
• Infarction
• Myocardial Infarction

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Leipzig

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Major Adverse Cardiac Event		30 months	No