Acute Myocardial Infarction Clinical Trial
Official title:
A Prospective Clinical Observation Study to Evaluate the Influence of Long Term Treatment of Pitavastatin on the Therapeutic Prognosis and Safety in Acute Myocardial Infarction
Statins are usually used in AMI patients due to its strong anti-lipidemic effect,
pleiotropic effect and tolerable safety profiles. Generally AMI patients are prescribed many
drugs concomitantly; there are some risks due to the drug interaction. Especially, statins
are reported to have many drug interactions, these might influence to therapeutic prognosis
and safety in AMI patients.
This study is conducted to administer the non-CYP3A4 metabolized statin, pitavastatin to AMI
patients over 1 year, and the results will be compared with the other results from the KAMIR
study which is expected to the large scale of AMI patients using statins be enrolled.
Finally, from that comparison, we will investigate the influence of the statins metabolism
by CYP3A4 to the therapeutic prognosis like death, major adverse cardiac events(MACE), and
major ADR of statins like CK increase, myalgia.
n/a
Time Perspective: Prospective
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