Acute Myeloid Leukemia Clinical Trial
Official title:
A Phase 1/1b Safety Study of PRGN-3006 Adoptive Cellular Therapy in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndrome
This study is to determine the safety and best dose of PRGN-3006 T Cells.
This is a single center, nonrandomized, investigator-initiated Phase 1/1b safety and
tolerability study. The safety and tolerability of PRGN-3006 T cells will be assessed
following intravenous administration of escalating doses in patients with relapsed or
refractory CD33-positive acute myeloid leukemia (AML) or higher risk myelodysplastic
syndromes (MDS).
The study will enroll in two phases: an initial dose escalation phase followed by a dose
expansion phase.
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