Xenon Against Postoperative Oxygen Impairment

Status Recruiting

Clinical Trial Summary

Acute lung injury (ALI) is the vital complication of Stanford type A aortic dissection. It is confirmed that Xenon has the significant protective effect on important organs and has no suppression on the cardiovascular system. Furthermore, our earlier trial has already clarified that static inflation with 50% Xenon during cardiopulmonary bypass could attenuate ALI for Standford A acute aortic dissection. However the protection effect was restricted for the limited time. Aimed to enhance the protection effect of Xenon, we designed this randomized trial that anesthesia with 50% xenon one hour before and after CPB and pulmonary static Inflation with 50%,75% and 100% Xenon during CPB respectively.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Acute Lung Injury
Lung Injury
Respiratory Distress Syndrome, Adult

Clinical Trial Details

NCT number	NCT02468531
Study type	Interventional
Source	Beijing Anzhen Hospital
Contact	Weiping Weiping, master
Phone	(86)010-6445-6329
Email	ch_eng9735@sina.com
Status	Recruiting
Phase	N/A
Start date	January 2015
Completion date	December 2017

View Details

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