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Clinical Trial Summary

The goal of this study is to determine if ibuprofen prior to exercise in the heat worsens biomarkers of acute kidney injury. Participants were given 600mg of ibuprofen or placebo (corn starch) 12- and 1-hour prior to running for 1-hour in a hot environment (35°C) at moderate intensity. Urine, plasma, and serum samples were collected pre-, post-, and 1hour post-exercise to assess biomarkers of acute kidney injury. This was a double blind, randomized crossover design, so that participants completed the alternate trial (ibuprofen or placebo) at least seven days later.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06247462
Study type Interventional
Source University of New Mexico
Contact
Status Completed
Phase Phase 1
Start date June 1, 2023
Completion date September 5, 2023

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