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Effect of Terlipressin on the Incidence of Early Postoperative Acute Kidney Injury in Liver Transplantation Patients

Acute Kidney Injury Clinical Trial

Official title:
Effect of Intraoperative Terlipressin on the Incidence of Early Postoperative Acute Kidney Injury in Liver Transplantation Patients: a Randomized, Double-blind, Placebo-controlled Study

Clinical Trial Summary

The goal of this clinical trial is to evaluate the effect of intraoperative terlipressin on the incidence of early postoperative acute kidney injury in deceased doner liver transplantation. Patients were randomly divided into experimental group and control group by numerical randomization table. The experimental group was injected with terlipressin perioperative and the control group was injected with placebo

Clinical Trial Description

acute kidney injury is a relatively common complication in patients with liver transplantation. Most centers have established prediction models for acute kidney injury after liver transplantation, but the incidence cannot be reduced through perioperative anesthesia management. As an vasopressin receptor agonist, terlipressin can increase blood pressure and improve kidney perfusion at the same time, and perioperative application may reduce the incidence of postoperative acute kidney injury ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06108362
Study type Interventional
Source Beijing Tsinghua Chang Gung Hospital
Contact Ziheng Qi, Doctor
Phone 15373598688
Email 469836626@qq.com
Status Recruiting
Phase Phase 4
Start date August 18, 2023
Completion date June 30, 2024
View Details
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