Melatonin for Prevention of Kidney Injury

Status Recruiting

Clinical Trial Summary

This study will evaluate the safety and effectiveness of melatonin for the prevention of antibiotic associated acute kidney injury in hospitalized patients.

Clinical Trial Description

Consenting subjects meeting inclusion and exclusion will be randomized to receive melatonin 5 mg daily or a matching placebo. Study subjects will be followed for the duration of hospitalization or discontinuation of broad spectrum antibiotics (vancomycin plus piperacillin/tazobactam). The primary outcome and secondary outcomes will be evaluated by the study team. ;

Study Design

Related Conditions & MeSH terms

Acute Kidney Injury
Adverse Drug Event
Drug-Related Side Effects and Adverse Reactions
Wounds and Injuries

Clinical Trial Details

NCT number	NCT05084196
Study type	Interventional
Source	Rutgers, The State University of New Jersey
Contact	Luigi Brunetti, PhD
Phone	908-595-2645
Email	luigi.brunetti@rutgers.edu
Status	Recruiting
Phase	Phase 3
Start date	June 5, 2023
Completion date	December 31, 2026

View Details

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