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Clinical Trial Summary

It is only between peak viremia and viral setpoint in natural acute HIV-1 infection that the immune response overwhelms viral replication resulting in a plasma viral load decline. The aim will be to characterize these immune responses, how they develop and their progeny. This will require the need to identify HIV-1 infected individuals before peak viremia and follow them to post viral setpoint. This protocol describes a pilot study to evaluate the feasibility of identifying, enrolling and following acute and early HIV-1 infected individuals from voluntary counselling and testing centres in Masaka, Bukomansimbi, Kalungu, Lwengo, Sembababule and Lyantonde districts.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT05372510
Study type Observational [Patient Registry]
Source MRC/UVRI and LSHTM Uganda Research Unit
Contact ANDREW OBUKU, PhD
Phone +256772623473
Email Andrew.Obuku@mrcuganda.org
Status Recruiting
Phase
Start date February 17, 2021
Completion date December 31, 2022