Severe Sepsis Clinical Trial
Official title:
Can the Venus 1000 Help Clinicians Treat Patients With Severe Sepsis or Acute Heart Failure? The CVP Trial
The purpose of this study is to evaluate the impact that the Venus 1000 non-invasive CVP system has on the management of emergency department (ED) patients with fluid sensitive conditions.
The ability to non-invasively, accurately, and continuously measure CVP to assess the
preload status of ED patients could lead to its inclusion into existing protocols (similar
to EGDT), or the development of novel protocols for the treatment of patients with fluid
sensitive conditions. The majority of other non-invasive measures of preload, such as
ultrasound of the inferior vena cava or the passive leg raise technique are not continuous
measures and require some type of effort or skill on the part of the clinician. Continuous
methods of assessing preload include CVP measurement through a central venous catheter,
esophageal Doppler monitoring, and pulse contour analysis via arterial catheter monitoring,
all of which involve invasive procedures.
The Venus CVP device is non-invasive and has continuous monitoring capabilities. The data
acquired from this project will allow us to determine whether emergency physicians will, in
practice, utilize the information provided by a non-invasive CVP monitoring device to assist
in the management of their patients with severe sepsis or acute HF.
;
Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Caregiver), Primary Purpose: Treatment
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