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Recombinant BNP on Heart and Renal Function in Acute Heart Failure

Acute Heart Failure Clinical Trial

Official title:
Effect of Recombinant BNP on Heart and Renal Function in Acute Decompensated Heart Failure Patients With Acute Renal Injury

Clinical Trial Summary

The purpose of this study is to evaluate the efficacy and safety of recombinant human B-type natriuretic peptide (rhBNP) on heart and renal function in patients with acute decompensated heart failure (ADHF) and acute renal injury (AKI).

Clinical Trial Description

Patients with acute decompensated heart failure (ADHF) and acute renal injury (AKI) will be randomized to receive standard of care with or without additional rhBNP.

Clinical heart function, LVEF, SCr, GFR and other laboratory parameters will be evaluated. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01625403
Study type Interventional
Source Shanghai Chest Hospital
Contact Fang Yuan
Email yuanfangysh@126.com
Status Recruiting
Phase Phase 2
Start date July 2012
Completion date December 2013
View Details
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