Acute Heart Failure Clinical Trial
Official title:
Heart & Diabetes - Feasibility Study
The main purpose of this study is to validate an intensive protocol of insulin infusion and subsequent subcutaneous insulin administration with the support of continuous glucose monitoring, in addition to reference finger-stick values.
Heart failure is a common disease (prevalence worldwide: 22 million; incidence worldwide: 2
million; prevalence in Italy: 750.000; incidence in Italy: 170.000), affecting 1-2% of
overall population and accounting for a significant proportion of healthcare costs.
Recurrent hospital admissions represent the majority of the disease-related cost. About
15-25% of patients with HF are diabetics: the presence of diabetes significantly worsens
prognosis in patients with heart failure and increases the risk of death by 30% compared to
subject without diabetes.
The intensive control of glycemia during acute heart failure is an objective of primary
importance, which can be obtained only with a proper strategy of patient management and with
a considerable organizational effort. In a shared protocol aimed at a tight control of
glycemia, the use of Continuous Glucose Monitoring (CGM) is expected to allow an easier
management of the patient and a more accurate implementation of the protocol.
The main purpose of this study is to validate an intensive protocol of insulin infusion and
subsequent subcutaneous insulin administration with the support of continuous glucose
monitoring, in addition to reference finger-stick values.
;
Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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