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IN-HOspital Program to systematizE Chest Pain Protocol (IN-HOPE) — In-Hope  

Acute Coronary Syndrome Clinical Trial

Official title:
Potential Impact in Clinical Practice of Early Exclusion Protocols for Acute Myocardial Infarction With High Sensitivity Troponin T in Different Scenarios (IN-HOspital Program to SystematizE Chest Pain Protocol-IN HOPE)

Clinical Trial Summary

Multicenter Nationwide Study for Analysis of the Potential Impact in Clinical Practice of Early Exclusion Protocols for Acute Myocardial Infarction with High Sensitivity Troponin T

Clinical Trial Description

Chest pain is the main clinical complaint in emergency room visits and represents the most common symptom of Acute Myocardial Infarction, which is the main cause of death in Brazil and worldwide. Although most patients with chest pain do not have a final diagnosis of AMI, they remain under observation until the diagnosis of AMI is excluded. The most current strategy recommended for rapid AMI exclusion uses high-sensitivity cardiac troponin T at time zero and one hour later. However, some points that have not yet been properly evaluated in previous studies can be evaluated in the current study: - Evaluation of the early exclusion protocol (0 -1 hour) in a Brazilian population - Evaluation of the early exclusion protocol (0 -1 hour) in isolation and associated with traditional risk scores (TIMI, GRACE, HEART and EDACS) - Systematic evaluation of the early exclusion protocol (0 -1 hour) in patients without chest pain but with a pre-defined condition of suspected AMI - Evaluation of the prognostic value of an isolated high-sensitivity cardiac troponin T < 5 ng/L in a diverse population. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04756362
Study type Observational
Source Hospital Samaritano Paulista
Contact
Status Completed
Phase
Start date July 23, 2020
Completion date July 31, 2022
View Details
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