Left Ventricular Dysfunction in Critically Ill Patients

Acute Coronary Syndrome Clinical Trial

— LEVEDYCIP  

Official title:

Left Ventricular Dysfunction in Critically Ill Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03787810
• Other study ID #: LEVEDYCIP
• Status: Completed
• Start date: May 28, 2018
• Est. completion date: February 20, 2020

Study information

• Verified date: September 2019
• Source: Sahlgrenska University Hospital, Sweden
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Left ventricular dysfunction is common in the critically ill. The aim of this study is to assess the incidence and prognosis of left ventricular dysfunction in critically ill patients.

Description:

Left ventricular dysfunction is common in the critically ill. A number of conditions can cause left ventricular dysfunction including myocardial infarction, septic cardiomyopathy, post resuscitation syndrome, takotsubo syndrome etc. A number of studies have assessed cardiac dysfunction in specific conditions (e.g. sepsis, cardiac arrest) but only a few studies have assessed cardiac dysfunction in a general ICU-population. The study will focus on diagnostics of the different types of cardiomyopathy and differentiating between ischemic and non-ischemic left ventricular dysfunction in a general ICU population. The aim of this study is to assess the incidence and prognosis of the different types of left ventricular dysfunction in critically ill patients. Our hypothesis is that left ventricular dysfunction is common in the critically ill and is associated with an increased risk of short-term death.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 428
• Est. completion date: February 20, 2020
• Est. primary completion date: February 20, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Admitted within 24 hours to the ICU

• Dysfunction of at least one organ system, defined as at least +1 point in SOFA-score.

Exclusion Criteria

-

Related Conditions & MeSH terms

• Acute Coronary Syndrome
• Cardiomyopathies
• Critical Illness
• Critically Ill
• Left Ventricular Dysfunction
• Takotsubo Cardiomyopathy
• Ventricular Dysfunction
• Ventricular Dysfunction, Left

Intervention

Diagnostic Test:
• Echocardiography
Echocardiography for assessment of left ventricular dysfunction

Locations

Country	Name	City	State
Sweden	Sahlgrenska University Hospital	Gothenburg	Västra Götalandsregionen

Sponsors (1)

Lead Sponsor	Collaborator
Sahlgrenska University Hospital, Sweden

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mortality	All cause mortality after admission to the ICU	30 days