The Impact of Early Surgery & Maintenance of Antiplatelet Therapy on

Status Completed

Clinical Trial Summary

Clinical Trial Description

Recent guidelines of the ACC/AHA suggest that elective non-cardiac surgery (NCS) should optimally be delayed one year after percutaneous coronary intervention (PCI) with drug-eluting stent (DES). Regarding the antiplatelet agents, dual antiplatelet therapy, or at least aspirin is recommended to be continued considering the relative risk of bleeding and stent thrombosis especially during the first 4 to 6 weeks after DES implantation. However, these recommendations are based upon insufficient and conflicting evidences.

The aim of our study was (1) to determine independent risk factors for postoperative adverse events and the strength of their association, (2) to assess the incidences of postoperative morbidities including major adverse cardiovascular and cerebral event as a function of time between PCI and surgery and (3) to compare bleeding amount and transfusion requirements between different intervals from PCI to surgery and durations of antiplatelet agent administration prior to surgery. To achieve this aim, we undertook a retrospective cohort study of the patients who underwent noncardiac surgery after PCI with DES. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02941588
Study type	Observational
Source	Seoul National University Hospital
Contact
Status	Completed
Phase	N/A
Start date	April 2016
Completion date	November 2017

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The Impact of Early Surgery and Maintenance of Antiplatelet Therapy on Intraoperative Bleeding and Major Adverse Cardiovascular Event After Percutaneous Coronary Intervention

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms