Acute Coronary Syndrome Clinical Trial
Official title:
Evaluating the Diagnostic Accuracy of 18F-sodium Fluoride Positron Emission Tomography for Identification of High-risk Vulnerable Coronary Atherosclerotic Plaque in Patients With Coronary Artery Disease
Recently, positron emission tomography(PET) using 18F-Sodium fluoride (NaF) showed promising
results for detecting vulnerable plaques in some pilot studies.
In this study, the investigators will evaluate the diagnostic accuracy of 18F-NaF PET for
non-invasively detecting vulnerable plaque, diagnosed by optical coherence tomography (OCT).
It has been well known that mechanism of acute coronary syndrome is plaque rupture and
occlusion of coronary artery by this plaque rupture. Until now, evaluation of vulnerable
plaque have been mainly performed with invasive imaging modalities such as optical coherence
tomography or intravascular ultrasound.
Recently, positron emission tomography(PET) using 18F-Sodium fluoride (NaF) showed promising
results for detecting vulnerable plaques in some pilot studies.
In this study, we will evaluate the diagnostic accuracy of 18F-NaF PET for non-invasively
detecting vulnerable plaque, diagnosed by optical coherence tomography (OCT).
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Observational Model: Case Control, Time Perspective: Prospective
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