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Clinical Trial Summary

DETERMINE is a multicenter, prospective, randomised, open, blinded end-point assessed (PROBE) trial, to evaluate two approaches of blood pressure (BP) management during mechanical thrombectomy for acute ischemic stroke due to an anterior large vessel occlusion.


Clinical Trial Description

This study have to objective to evaluate the efficacy of an individualized BP control during mechanical thrombectomy (regardless of the sedation modality), by maintaining a mean arterial pressure (MAP) within 10% of the first MAP measured in the angiography suit, compared to the standard BP management, on the 3-month functional outcome. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04352296
Study type Interventional
Source Fondation Ophtalmologique Adolphe de Rothschild
Contact Amélie Yavchitz
Phone +33148036454
Email ayavchitz@for.paris
Status Recruiting
Phase N/A
Start date March 8, 2021
Completion date November 20, 2024

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