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NCT04947748 Clinical Trial

Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous

Acute Appendicitis Clinical Trial

Official title:
Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04947748
Other study ID # 1
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date November 1, 2020
Est. completion date December 31, 2021

Study information
Verified date June 2021
Source North Estonia Medical Centre
Contact Edgar Lipping, MD
Phone 6171520
Email edgar.lipping@regionaalhaigla.ee
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial therapy after surgery in complicated appendicitis.

Recruitment information / eligibility
Status Recruiting
Enrollment 100
Est. completion date December 31, 2021
Est. primary completion date December 31, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: Patients diagnosed with acute appendicitis and are candidates for laparoscopic appendectomy. Exclusion Criteria: Patients with compromised immune system (HIV, diabetes), ongoing or completed radio-chemotherapy in past 5 years, prosthetic heart valve, vascular prosthesis, pregnancy.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Oral versus intravenous administration of antibacterial treatment
Mode of administration of antibacterial treatment

Locations
Country Name City State
Estonia North Estonia Medical Centre Tallin

Sponsors (2)
Lead Sponsor Collaborator
North Estonia Medical Centre Tartu University Hospital

Country where clinical trial is conducted

Estonia, 

Outcome
Type Measure Description Time frame Safety issue
Primary Infectious complications 30 days
See also
  Status Clinical Trial Phase
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Completed NCT04649996 - Variation in Acute Appendicitis During COVID-19 Pandemic in Italy
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Completed NCT04030741 - Non-operative Treatment of Acute Non-perforated Appendicitis Phase 2/Phase 3
Recruiting NCT04860570 - Are Double-ring Wound-edge Protectors Effective for Preventing Superficial Surgical Site Infection After Open Appendectomy?
Withdrawn NCT05724628 - Non-operative vs. Operative Management of Acute Appendicitis in Vulnerable Patient Populations Phase 1
Completed NCT01024439 - Transumbilical Single Incision Versus Conventional Three Incisions Laparoscopic Appendicectomy N/A
Completed NCT02714023 - Water And Saline Head-to-head In The Blinded Evaluation Study Trial N/A
Active, not recruiting NCT03324165 - Comparing Proposed Algorithm and Current Practice in the Evaluation of Suspected Appendicitis N/A
Active, not recruiting NCT01022567 - Appendicectomy Versus Antibiotics in the Treatment of Acute Uncomplicated Appendicitis N/A
Not yet recruiting NCT06051825 - Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute Appendicitis
Not yet recruiting NCT06059365 - Clinical Trial for a Outpatient Clinical Management for Complicated Acute Appendicitis N/A
Completed NCT04615728 - MANAGEMENT OF APPENDICITIS DURING THE COVID-19 PANDEMIC
Terminated NCT04207645 - Modification and Validation of the RIPASA Score for Diagnosis of Acute Appendicitis
Not yet recruiting NCT02789865 - Clinical Trial Comparing ERAT vs Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis Phase 2
Completed NCT02731924 - Point of Care Ultrasound for Evaluation of Suspected Appendicitis in the Emergency Department
Completed NCT05104346 - Presentation and Outcomes of Acute Appendicitis During COVID Pandemic N/A
Completed NCT03886896 - Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy Phase 4
Not yet recruiting NCT01720082 - Laparoscopic Appendectomy by Multi-port vs Single Port. Phase 3
Completed NCT01348464 - A Trial on Laparoscopic Appendectomy Versus Single Port Appendectomy N/A