Clinical Trials Logo

Clinical Trial Summary

Laparoscopic appendectomy (LA) is a widespread surgical procedure. Patients may develop considerable postoperative pain and dyspepsia resulting in prolong in-hospital stay. Almost 10% of patients develop postoperative complications. Enhanced recovery after surgery (ERAS) program has proven its effectiveness in elective surgery and can theoretically improve outcomes of LA. To date there is no ERAS program for LA. The aim of the study was to investigate the safety and efficacy of a modified ERAS protocol in LA.


Clinical Trial Description

A modified ERAS (mERAS) protocol was investigated. The study is a prospective, randomized nonblinded. All patients underwent LA. Modified ERAS protocol included patient informing, limitation of drainage use; intraperitoneal anesthesia with long-acting anesthetics; low-pressure pneumoperitoneum; early mobilization and oral nutrition. Pain level was assessed in rest using visual analogue scale (VAS). The primary endpoint was postoperative length of stay (pLOS). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03754777
Study type Interventional
Source Pirogov Russian National Research Medical University
Contact
Status Completed
Phase N/A
Start date July 1, 2017
Completion date February 1, 2018

See also
  Status Clinical Trial Phase
Completed NCT01697059 - Initial Antibiotics and Delayed Appendectomy for Acute Appendicitis N/A
Completed NCT04649996 - Variation in Acute Appendicitis During COVID-19 Pandemic in Italy
Completed NCT04387370 - The Use of the Hem-o-lok Clip in Appendectomy: Single or Double?
Completed NCT04030741 - Non-operative Treatment of Acute Non-perforated Appendicitis Phase 2/Phase 3
Recruiting NCT04860570 - Are Double-ring Wound-edge Protectors Effective for Preventing Superficial Surgical Site Infection After Open Appendectomy?
Withdrawn NCT05724628 - Non-operative vs. Operative Management of Acute Appendicitis in Vulnerable Patient Populations Phase 1
Completed NCT01024439 - Transumbilical Single Incision Versus Conventional Three Incisions Laparoscopic Appendicectomy N/A
Completed NCT02714023 - Water And Saline Head-to-head In The Blinded Evaluation Study Trial N/A
Active, not recruiting NCT03324165 - Comparing Proposed Algorithm and Current Practice in the Evaluation of Suspected Appendicitis N/A
Active, not recruiting NCT01022567 - Appendicectomy Versus Antibiotics in the Treatment of Acute Uncomplicated Appendicitis N/A
Not yet recruiting NCT06051825 - Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute Appendicitis
Not yet recruiting NCT06059365 - Clinical Trial for a Outpatient Clinical Management for Complicated Acute Appendicitis N/A
Recruiting NCT04947748 - Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous N/A
Completed NCT04615728 - MANAGEMENT OF APPENDICITIS DURING THE COVID-19 PANDEMIC
Terminated NCT04207645 - Modification and Validation of the RIPASA Score for Diagnosis of Acute Appendicitis
Not yet recruiting NCT02789865 - Clinical Trial Comparing ERAT vs Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis Phase 2
Completed NCT02731924 - Point of Care Ultrasound for Evaluation of Suspected Appendicitis in the Emergency Department
Completed NCT05104346 - Presentation and Outcomes of Acute Appendicitis During COVID Pandemic N/A
Completed NCT03886896 - Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy Phase 4
Not yet recruiting NCT01720082 - Laparoscopic Appendectomy by Multi-port vs Single Port. Phase 3