Plain Magnetic Resonance (MR) in the Assessment of Patients With Acute Abdomen

Acute Abdomen Clinical Trial

Official title:

Assessment of Patients With Nontraumatic Acute Abdominal Pain With Plain MR of the Abdomen - a Comparison With CT

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT01044173
• Other study ID #: N-20090033
• Status: Withdrawn
• Phase: N/A
• First received: January 6, 2010
• Last updated: January 29, 2017
• Start date: October 2011
• Est. completion date: October 2012

Study information

• Verified date: January 2017
• Source: Zealand University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

At present, CT is the gold standard in the assessment of patients with acute abdomen. Yet, one CT of the abdomen exposes patients to a radiation dose equivalent to several years of background radiation. MR can be expected to yield the same information without ionizing radiation, but tends to be more time consuming. In this study, patients with nontraumatic acute abdominal pain referred to CT of the abdomen by the department of surgery will also have performed an additional MR scan covering the entire abdomen with few fast imaging sequences in approximately 15min. CT is the diagnostic test. The MR scan is only used for scientific purposes. It will be evaluated by a radiologist blinded for the results of the CT scan. Fourteen days after admission, a final diagnosis is established based on clinical, peroperative, pathological and lab. findings. The performance of CT and MR will then be compared. The investigators hypothesize that MR can provide a diagnostic accuracy comparable to CT.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: October 2012
• Est. primary completion date: September 2012
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Signed informed consent form

• Age > 18 years old

• Nontraumatic acute abdomen

• Weight < 120kg

• Can keep apnoea for 15s

• Surgeon in charge considers patient fit for participation in study

Exclusion Criteria:

• Contraindications of MRI

• Suspicion of acute vascular disease

• Severe cardial or pulmonal insufficiency

• Pregnancy

• Untreated psychiatric illness

Related Conditions & MeSH terms

• Abdomen, Acute
• Acute Abdomen

Intervention

Device:
• MR scan
axial and coronal free breathing HASTE sequences 3D T1 weighted gradient echo breathhold

Locations

Country	Name	City	State
Denmark	Koege Sygehus	Koege

Sponsors (1)

Lead Sponsor	Collaborator
Zealand University Hospital

Country where clinical trial is conducted

Denmark, 

References & Publications (1)

Stoker J. Magnetic resonance imaging and the acute abdomen. Br J Surg. 2008 Oct;95(10):1193-4. doi: 10.1002/bjs.6378. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	diagnostic accuracy of CT vs. MR		14 days