Clinical Trials Logo
  1. Home
  2. Acute Abdomen
  3. NCT04196244

Intravenous Contrast Computed Tomography Versus Native Computed Tomography in Patients With Acute Abdomen and Impaired Renal Function — INCARO  

Acute Abdomen Clinical Trial

Official title:
INtravenous Contrast Computed Tomography Versus Native Computed Tomography in Patients With Acute Abdomen and Impaired Renal functiOn (INCARO) - a Multicentre, Open-label, Randomised Controlled Trial

Clinical Trial Summary

Computer tomography (CT) is the primary imaging option for acute abdominal pain in adults. Intravenous (IV) contrast media is used to improve the CT quality. In patients with impaired renal function, post-contrast acute kidney injury (PC-AKI) has remained a significant concern. Modern retrospective studies have shown no association between worsened baseline renal function and IV-contrast CT. However, no randomised controlled trial has been done to conclude this. The INCARO (INtravenous Contrast computed tomography versus native computed tomography in patients with acute Abdomen and impaired Renal functiOn) trial is a multicentre, open-label, parallel group, superiority, individually randomised controlled trial comparing IV-contrast enhanced CT to native CT in patients with impaired renal function. Patients requiring emergency abdominal or body CT with eGFR 15-45 ml/min/1.73 m2 are included in the study. The primary outcome is a composite outcome of all-cause mortality or renal replacement therapy within 90 days from CT.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04196244
Study type Interventional
Source Helsinki University Central Hospital
Contact
Status Recruiting
Phase Phase 4
Start date September 18, 2020
Completion date September 2033
View Details
See also
  Status Clinical Trial Phase
Withdrawn NCT01044173 - Plain Magnetic Resonance (MR) in the Assessment of Patients With Acute Abdomen N/A
Active, not recruiting NCT06154603 - Upper Gastrointestinal Perforations: a Nationwide Registry-based Study
Recruiting NCT06182488 - Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Emergency Laparotomy N/A
Completed NCT05295251 - The Commonest Medical, Surgical, and Oncological Causes of Acute Abdomen in Adults With COVID-19. A Prospective Observational Study.
Not yet recruiting NCT05407922 - Laparoscopic Value in the Management of Acute Abdomen During Pregnancy
Recruiting NCT02467959 - Diagnostic Accuracy of Emergency Physician Performed Bedside Ultrasound in Suspected Acute Appendicitis N/A
Completed NCT01911702 - Different Fluidic Strategy in Patients With Acute Abdomen : The Sure Volume Phase 2
Completed NCT00870766 - Computer Tomography (CT) Trial of Acute Abdomen N/A
Completed NCT05419440 - Laparoscopic Drainage Versus Interventional Radiology In Management Of Appendicular Abscess : N/A
Completed NCT05004532 - Transversus Abdominis Plane Block in Acute Appendicitis Pain Managment
Completed NCT05591495 - The Role of Laparoscopy in Upper Abdominal Surgical Emergencies in Adults: A Retrospective Observational Study.
Completed NCT03262025 - Primary Cecal Pathologies Presenting as Acute Abdomen N/A
Active, not recruiting NCT03549624 - Standardized Perioperative Management of Patients Operated With Acute Abdominal Surgery in a High-risk Emergency Setting
Recruiting NCT06320886 - Role of Ultrasonography in Acute Abdomen in Adults in Correlation to Computed Tomography Scan
Completed NCT01982708 - A Prospective Study of a Haptic Device Evaluation of the Acute Abdomen N/A
Not yet recruiting NCT04577339 - The Best Care for Abdominal Emergencies Study
Completed NCT04662242 - The Prognostic Impact of Selenium On Critical Surgical Patients Phase 4
Completed NCT04966780 - Refeeding Like Syndrome in Acute Disease
Enrolling by invitation NCT03096665 - Effectiveness of Point of Care Blood Analysis Obtained From Skin Puncture Blood N/A