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Acne clinical trials

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NCT ID: NCT02152865 Completed - Acne Clinical Trials

Clinical Trial of Lupeol for Mild-moderate Acne

Start date: December 2009
Phase: N/A
Study type: Interventional

For the chemical lupeol isolated from eggplant, we applied it to one side of face, and applied vehicle control to another side for 8 -weeks. The study was performed in a 8-week, randomized controlled, split face fashion. Investigators evaluated safety and efficacy during baseline, 2 weeks, 4weeks, and 8 weeks after beginning of study.

NCT ID: NCT01951417 Completed - Acne Clinical Trials

Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris

Start date: October 2013
Phase: Phase 4
Study type: Interventional

This is an open-label, multi-center study to be conducted in the United States. The study will examine the change in lesion count in subjects using Epiduo® Gel Pump (once daily) in conjunction with Cetaphil® DermaControlâ„¢ Foam Wash (twice daily) and Moisturizer SPF 30 (once daily). Subjects with a clinical diagnosis of mild or moderate acne who are eligible for treatment with Epiduo® in accordance with the currently approved product labeling and who meet other inclusion/exclusion criteria are to be enrolled in the study and receive the study products for 8 weeks. Efficacy and safety assessments include: complete lesion counts, cutaneous irritation assessment, end of study treatment questionnaire, photographic evaluation for oiliness, skin tone, and P Acnes, hydration assessment, barrier function assessment, treatment compliance, and adverse event assessment.

NCT ID: NCT01948570 Completed - Acne Clinical Trials

Clinical Study for the Evaluation of P-3075 Cream on Acne Treatment

ANTI-ACNE
Start date: March 2013
Phase: N/A
Study type: Observational [Patient Registry]

Primary end point of the study is the clinical and non-invasive instrumental evaluation of the activity of P-3075 cream on subjects with acne: 20 subjects with a mild/moderate grade and 20 subjects with a moderately severe/severe grade, according to Cunliffe' classification. Secondary end-points are the cosmetic acceptability and efficacy evaluation by the volunteers and the local tolerability assessed by the investigator and the subjects.

NCT ID: NCT01929057 Completed - Acne Clinical Trials

Evaluation of the Role of Propionibacterium Acnes in the Inflammatory Lesions Associated With Acne Vulgaris

Start date: August 2013
Phase:
Study type: Observational

The purpose of this study is to determine the response of acne patients and healthy control patients to the P. acnes bacteria. Half a tube of blood will be drawn from all participants to determine whether or not they have antibodies to the P. acnes bacterium. Anywhere from 1 to 4 skin biopsies of acne pimples or normal control skin will be taken from all subjects for further analysis in the lab to determine whether the inflammation in these pimples can be reduced using anti-P.acnes antibodies.

NCT ID: NCT01835210 Completed - Quality of Life Clinical Trials

Effect of Acne Vulgaris on Quality of Life of Teenagers Compared to Parent Perceived Effect on Quality of Life

Start date: August 2012
Phase: N/A
Study type: Observational

Acne vulgaris is a common problem in the adolescent community. Past research has shown that acne affects teenager's self-esteem and mood. However, no research has evaluated the parent perception of their teenager's acne in comparison to the severity of acne and the patient's own reported quality of life. It is hypothesized that parents of teenagers underestimate how much acne vulgaris affects their teenager's skin disease-related quality of life. Also that teenager's perception of the severity of their acne is greater versus their parent's perception. We believe that increased acne severity based on clinician assessment will correlate with worse quality of life. Teenagers between 12 and 17 years old with a diagnosis of acne by a pediatric dermatologist will be enrolled in this study. The study consists of 1 visit, questions regarding demographics, assessment of the teen's acne, the Skindex-Teen quality of life survey (modified for parents), and 2 Likert scales will be completed. In addition, the clinician will score the teen's acne using the standardized Investigator Global Assessment tool. Statistical analysis will compare teen subject answers to the Skindex-Teen with their parent's answers. Also analyzed will be the severity of acne and differences between the clinician IGA score and Skindex-Teen responses

NCT ID: NCT01796665 Completed - Acne Clinical Trials

A Study to Compare Clindamycin Phosphate and Benzoyl Peroxide Topical Gel 1.2%/2.5% to Acanya® Topical Gel in the Treatment of Acne Vulgaris

Start date: February 2012
Phase: Phase 3
Study type: Interventional

The objective of this study was to evaluate the efficacy and safety of Perrigo's test formulation of Clindamycin Phosphate and Benzoyl Peroxide Topical Gel 1.2%/2.5% compared to the already marketed formulation, Acanya gel in patients with acne vulgaris.

NCT ID: NCT01701024 Completed - Acne Clinical Trials

Clinical Study to Test the Efficacy and Safety of ACYC to Treat Moderate to Severe Acne

ACYC
Start date: October 2012
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to compare the efficacy and safety and tolerability of ACYC Gel and vehicle in the treatment of subjects with Acne Vulgaris.

NCT ID: NCT01688531 Completed - Acne Clinical Trials

A Pilot Study to Investigate Filiation Between Primary and Secondary Lesions in Acne Patients

Start date: August 2012
Phase: Phase 1
Study type: Interventional

Exploratory, international, multi-centre, randomized, investigator blinded study in acne

NCT ID: NCT01657110 Completed - Acne Clinical Trials

Pilot Study to Evaluate Tea Tree Oil Gel for Facial Acne

Start date: December 2012
Phase: Phase 2
Study type: Interventional

Mild to moderate facial acne is an extremely common disease of teenagers and young adults. This pilot study will investigate whether treatment with a gel containing tea tree oil reduces numbers of acne lesions and improves acne in twenty otherwise healthy consenting participants. The hypothesis is that treatment with tea tree oil gel will result in a significant improvement in acne after 12 weeks of treatment.

NCT ID: NCT01556698 Completed - Acne Vulgaris Clinical Trials

Study of NVN1000 Topical Gel and Topical Gel Vehicle in the Treatment of Moderate to Severe Acne Vulgaris

Start date: July 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The primary objective of this study is to compare the tolerability, safety and efficacy of NVN1000 Topical Gel and Topical Gel Vehicle in the treatment of subjects with moderate to severe acne vulgaris.