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Acne clinical trials

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NCT ID: NCT02515305 Completed - Acne Clinical Trials

Comparative Safety and Efficacy of Two Treatments in the Treatment of Acne Vulgaris

Start date: July 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of Perrigo's product to an FDA approved product for the treatment acne vulgaris

NCT ID: NCT02457520 Completed - Acne Clinical Trials

ABSORICA in Patients With Severe Recalcitrant Nodular Acne

Start date: January 21, 2015
Phase: Phase 4
Study type: Interventional

This is an uncontrolled, open-label study being conducted in approximately 200 healthy males, non-pregnant, non-nursing females, age 12 to 45 years, with severe recalcitrant nodular acne. ABSORICA® (isotretinoin) capsules 0.5 mg/kg/day will be administered for 4 weeks followed by 1.0 mg/kg/day for 16 weeks. Female subjects consenting to use two forms of birth control or abstinence are included.

NCT ID: NCT02457000 Completed - Healthy Clinical Trials

Sleep, Circadian Rhythm & Skin Health

Start date: March 2015
Phase:
Study type: Observational

The purpose of this study is to explore the mechanisms behind how sleep quality may affect skin aging, skin integrity and skin disease.

NCT ID: NCT02307266 Completed - Acne Clinical Trials

Patient Education in Adherence on Acne (PEAce)

Start date: November 2014
Phase: Phase 4
Study type: Interventional

This is a multi-center, randomised and controlled study in subjects with acne vulgaris. The main objective of this study is to evaluate the effect of a supplementary patient education intervention (in addition to the standard-of-care patient education) on treatment adherence and satisfaction among acne patients receiving once-daily EpiduoTM gel treatment in primary care clinics.

NCT ID: NCT02250859 Completed - Acne Clinical Trials

A Pharmacokinetic Study of Minocycline in Male and Female Volunteers

Start date: September 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the pharmakokinetic profile of Minocycline in FMX-101 4% foam product in male and female some of which are with acne

NCT ID: NCT02249767 Completed - Acne Clinical Trials

Bioequivalence Study of Tretinoin Gel 0.05% to Brand Tretinoin Gel

Start date: November 2013
Phase: Phase 3
Study type: Interventional

This was a double-blind, randomized, three-treatment, parallel study. Normal, healthy male and female children and adults (i.e., ages 12 to 40 years) with at least Grade 2 (i.e., mild severity) acne vulgaris were treated on the full face once daily for 84 days with the Tretinoin Gel 0.05%, Brand (tretinoin) Gel 0.05%, or Gel Vehicle. Acne lesions were graded by a single blinded observer at screening and at Weeks 0 (i.e., baseline), 2, 4, 8, and 12 at each location.

NCT ID: NCT02207738 Completed - Acne Clinical Trials

Comparison of Efficacy Between Fractional Microneedling Radiofrequency and Bipolar Radiofrequency for Acne Scar

Start date: January 2012
Phase: N/A
Study type: Interventional

Compare the efficacy and safety profile of microneedling radiofrequency and that of bipolar radiofrequency treatment for acne scar.

NCT ID: NCT02205892 Completed - Acne Clinical Trials

Clinical Study for Topical Lupeol in Acne

Start date: August 2014
Phase: N/A
Study type: Interventional

Double-blind, randomized,4-week small-scale clinical trial for lupeol in the treatment of inflammatory and non-inflammatory acne lesions in split face fashion

NCT ID: NCT02180425 Completed - Acne Clinical Trials

The Lipid Profile of the Skin Surface in Acne

Acne
Start date: November 2013
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the differences in the skin lipid profile of patients with and without acne. Secondly, the goal is to learn more about what the effects of retinoinds (topical and systemic) are on the the skin lipid profile. We hypothesize that the skin lipid profile of subjects with acne will be lower in inflammatory lipids in comparison to subjects without acne.

NCT ID: NCT02173054 Completed - Acne Clinical Trials

An Efficiency of a Moisturizer Containing Licochalcone A, L-carnitine and 1,2-decanediol With Adapalene Gel in Acne

Start date: July 2014
Phase: Phase 3
Study type: Interventional

Acne is an inflammation of sebaceous glands and follicles. Applying topical treatments such as adapalene gel may cause irritant adverse effects. Hence, using a moisturizer is another way to protect or relieve this undesirable event. Moisturizers that have anti-inflammatory property could reduce irritant effects, emergent from using topical treatment and also reduce severity of acne. Research teams chose an adapalene gel to act as topical treatment for curing acne. It has anti-inflammatory and comedolytic effects and has fewer side effects than other groups of topical retinoic acids. However, peeling skin, redness skin, tingling sensation or itching sensation may occur if they are continually used for a long period. Thus, for the purpose of studying the efficacy of moisturizer containing licochalcone A, L-carnitine and 1,2-decanediol in reducing irritant effect of using adapalene gel (Licochalcone A has anti-inflammatory effect, L-carnitine decrease sebum production and 1,2-decanediol has anti-bacterial effect).