Can PRP Reduce Pro-Inflammatory Biomarkers Following ACL Injury

Status Withdrawn

Clinical Trial Summary

The purpose of this single-center, double-blinded randomized control trial with prospective data collection is to assess the ability of platelet rich plasma (PRP) treatment to reduce the level of pro-inflammatory synovial fluid biomarkers following an acute anterior cruciate ligament (ACL) tear. The study will collect and analyze synovial fluid of patients presenting with an acute anterior cruciate ligament (ACL) tear with a second synovial fluid sampling at the time of surgery. It will compare synovial fluid biomarker levels between those receiving an intra-articular Platelet Rich Plasma (PRP) injection versus an intra-articular saline injection serving as a control. Post-operative clinical outcomes will also be assessed, including post-operative pain levels, incidence of post-operative knee stiffness and patient reported outcome scores.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

ACL - Anterior Cruciate Ligament Rupture
ACL Injury
Anterior Cruciate Ligament Injuries
Rupture

Clinical Trial Details

NCT number	NCT03389685
Study type	Interventional
Source	NYU Langone Health
Contact
Status	Withdrawn
Phase	Phase 2
Start date	September 9, 2018
Completion date	February 2024

View Details

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