Clinical Trials Logo
  1. Home
  2. ACL Injury
  3. NCT04901858

Knee Aspiration and High Definition MRI for ACL Injury

ACL Injury Clinical Trial

Official title:
Pilot Study Into the Structural Local Molecular Environment Following an ACL Injury

Clinical Trial Summary

The aim of this pilot study is to understand the biological changes that occur within the knee joint following injury to the anterior cruciate ligament (ACL). This will be achieved through aspiration and analysis of the haemarthrosis which fills the knee following injury. The study will look at inflammatory and healing responses using DNA, RNA and protein analysis. This, combined with high resolution imaging of the knee and surrounding soft tissue structures, may enable a more patient specific approach to treatment of ACL injury.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04901858
Study type Interventional
Source Cambridge University Hospitals NHS Foundation Trust
Contact Stephen McDonnell
Phone 01223 217551
Email sm2089@cam.ac.uk
Status Recruiting
Phase N/A
Start date November 22, 2019
Completion date November 2024
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04519801 - BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft N/A
Withdrawn NCT03389685 - Can PRP Reduce Pro-Inflammatory Biomarkers Following ACL Injury Phase 2
Recruiting NCT04958733 - Does Bone Grafting at the Time of Bone-Patellar Tendon-Bone ACL Reconstruction Reduce the Incidence of Post-operative Anterior Knee Pain: A Randomized Controlled Clinical Study N/A
Terminated NCT04101682 - Continuous Vs Single Shot Block After ACL Early Phase 1
Not yet recruiting NCT05374382 - A Prehab Strengthening Program Prior to ACL Surgery on Lower Limb Structure and Function N/A
Not yet recruiting NCT04068701 - Real-time Sensorimotor Feedback for Injury Prevention in Males Assessed in Virtual Reality N/A
Recruiting NCT03479775 - Muscle Function and Traumatic Knee Injury in Sports
Not yet recruiting NCT05498285 - Post-ACL Reconstruction Rehab UPSCALER App RCT HPUPM N/A
Recruiting NCT05461625 - ACL Reconstruction With/Without ALL Reconstruction N/A
Active, not recruiting NCT03491046 - Molecular Imaging Assessment of ACL Viability N/A
Withdrawn NCT04342000 - The Effect of Movement Education on Jumping/Landing Quality in High School Athletes N/A
Completed NCT04993339 - Clinical Outcomes of ACL Reconstruction Augmented by an Injectable Osteoconductive/Osteoinductive Compound Phase 3
Withdrawn NCT03614351 - Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery N/A
Withdrawn NCT03670550 - Dynamic ACL Brace: In Vivo Kinematics N/A
Recruiting NCT06206200 - The Effect of Cognitive Dual-task Rehabilitation on Arthrogenic Muscle Responses After ACL Reconstruction N/A
Active, not recruiting NCT06167343 - Comparison of Semitendinosus and Quadriceps Grafts for Anterior Cruciate Ligament Reconstruction N/A
Completed NCT04541940 - TeleRehabilitation Following ACL Reconstruction N/A
Terminated NCT03497780 - Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:
Completed NCT04967937 - Neuromuscular Training Improves Single-Limb Stability N/A
Completed NCT02602561 - Effects of HMB Supplementation on Recovery Following ACL Surgery N/A