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Abuse, Drug clinical trials

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NCT ID: NCT04451863 Not yet recruiting - Pain Clinical Trials

Analgesic and Subjective Effects of Terpenes

Start date: June 2021
Phase: Phase 1
Study type: Interventional

The purpose of this research is to assess the analgesic and subjective effects of terpenes administered alone and in combination of THC.

NCT ID: NCT04385082 Not yet recruiting - Pain Clinical Trials

Cannabis Effects as a Function of Sex (CanSex)

CanSex
Start date: June 2021
Phase: Phase 1
Study type: Interventional

The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-related effects between men and women

NCT ID: NCT04110535 Completed - Abuse, Drug Clinical Trials

Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users

Start date: June 23, 2015
Phase: Phase 1
Study type: Interventional

A double-blind, randomized crossover study to assess the subjective abuse potential of intravenous remimazolam compared to midazolam and placebo in recreational CNS depressant users

NCT ID: NCT03757559 Completed - Abuse, Drug Clinical Trials

A Trial to Evaluate the Abuse Potential of 3 Doses of GRT6005 in Adult Non-dependent Recreational Opioid Users

Start date: April 15, 2013
Phase: Phase 1
Study type: Interventional

The primary objective of this study was to evaluate the abuse potential of single doses of cebranopadol (GRT6005) relative to hydromorphone (immediate-release formulation [IR] and placebo in 48 non-dependent recreational opioid users. Secondary objectives were to evaluate the abuse potential of hydromorphone IR compared to placebo (trial validation), to evaluate the safety and tolerability of single doses of cebranopadol (200, 400, and 800 micrograms), and to evaluate pharmacokinetics (PK) of cebranopadol and optionally some of its metabolites.

NCT ID: NCT03679949 Recruiting - Pain Clinical Trials

Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia

Start date: April 1, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-liability effects of a sub-threshold dose of a commonly used analgesic.