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Abscess clinical trials

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NCT ID: NCT02066818 Completed - Pain Clinical Trials

Injectable Lidocaine Versus Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses

Start date: January 2008
Phase: Phase 0
Study type: Interventional

Local anesthesia used for incision and drainage of abscesses is known to be painful. We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I&D) of skin abscesses. Local injection of lidocaine provided similar analgesia compared to the lidocaine/tetracaine patch during I&D of skin abscesses in the Emergency Department. Pain at presentation and following the procedure was similar in both groups.

NCT ID: NCT02032914 Completed - Clinical trials for Cryptogenic Pyogenic Liver Abscess

Prevalence of Colon Cancer in Pyogenic Liver Abscess

Start date: January 2014
Phase: Phase 4
Study type: Observational [Patient Registry]

Although a proportion of pyogenic liver abscess may originated from colonic mucosal lesions, the prevalence of colonic neoplasm in the patients with pyogenic liver abscess are still not evaluated yet. Thus, our group will find the prevalence of colonic neoplasm in the group of cryptogenic pyogenic liver abscess by colonoscopic examination.

NCT ID: NCT02024867 Completed - Abscess Clinical Trials

Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage

Start date: February 2010
Phase: N/A
Study type: Interventional

The objective of this study is to determine if there is a difference in treatment failures and recurrent skin infections when patients are given 3 or 10 days of antibiotics for uncomplicated skin abscesses after they have been surgically drained.

NCT ID: NCT02024282 Completed - Sepsis Clinical Trials

Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care

ERNIE2
Start date: January 2013
Phase: N/A
Study type: Interventional

Acute illness is the most common presentation of children attending ambulatory care settings. Serious infections (e.g. meningitis, sepsis, pyelonephritis, pneumonia) are rare, but their impact is quite large (increased morbidity, mortality, induced fear in parents and defensive behaviour in clinicians). Early recognition and adequate referral of serious infections are essential to avoid complications (e.g. hearing loss after bacterial meningitis) and their accompanied mortality. Secondly, we aim to reduce the number of investigations, referrals, treatments and hospitalisations in children who are diagnosed with a non-serious infection. Apart from the cost-effectiveness, this could lead to less traumatic experiences for the child and less fear induction for the concerned parent. Finally, we aim to support the clinicians to rationalise their antibiotic prescribing behaviour, resulting in a reduction of antibiotic resistance in the long run.

NCT ID: NCT01911351 Active, not recruiting - Abscess Clinical Trials

Nitrous Oxide Use in Minor Procedures

Start date: July 2013
Phase: N/A
Study type: Interventional

Title: High-concentration continuous flow nitrous oxide use for procedural-induced pain or anxiety during pediatric minor procedures. Objective: To assess whether the use of high-concentration continuous flow nitrous oxide in addition to standard management increases the comfort level in pediatric patients undergoing minor procedures compared to standard management alone.

NCT ID: NCT01897675 Completed - Cutaneous Abscess Clinical Trials

A Comparison of Techniques for Treating Skin Abscesses

LoopDrainage
Start date: August 2013
Phase: N/A
Study type: Interventional

Management of abscesses traditionally involves incision and drainage (I&D). Abscesses are frequently are "packed" or stented open with the presence of a wick, and traditional care requires re-visits every 2-3 days to have the packing removed and replaced, until finally the abscess cavity has closed, usually 1-2 weeks after initial presentation. Recently there have been attempts to employ less invasive techniques for abscess management. One novel technique, "loop drainage", has been reported in case reports/case series for management of a variety of types of abscesses in the surgical subspecialty literature. We propose to conduct a randomized prospective study comparing the efficacy of the loop drainage technique with the traditional incision and drainage technique of abscess management. Patients presenting to the main or urgent care areas of the Emergency Department at Boston Medical Center for treatment of an abscess will be considered for enrollment as potential subjects. After the treating clinician identifies the patient as an appropriate subject, a Research Associate (RA) will approach the patient and obtain written informed consent to enroll in the study. The subject will then be randomized to the management arm of either loop drainage or traditional I&D. The clinician will fill out a data sheet describing the abscess characteristics, and then perform either loop drainage or incision and drainage, depending on randomization and the subject will fill out a satisfaction survey. Fourteen days after initial visit, subjects will return for follow-up. The subject will fill out a satisfaction survey, and a study investigator blinded to the treatment group will assess the subject for abscess resolution, cosmetic outcome, number of follow-up visits, and complications. The study investigators will then compare outcomes between the two study groups.

NCT ID: NCT01881997 Withdrawn - Abscess Clinical Trials

Pain Management in ED for Incision and Drainage of Abscess

Start date: June 2011
Phase: Phase 4
Study type: Interventional

Patients presenting with painful procedures in the Emergency Department (ED) have been shown to frequently have inadequate pain management. The incision and drainage (I&D) of an abscess is a common procedure that is viewed by many emergency physicians as only requiring a localized anesthetic for pain management. However, it has been documented in previous research that there can be disconnect between what emergency medicine physicians interpret as painful and what patients experience as pain. A trial will be conducted to focus on use of intramuscular (IM) Fentanyl as an intervention to help alleviate pain associated with the incision and drainage of an abscess. This is a procedure that rarely receives systemic opioids. This double blinded protocol will randomize a total of 50 patients patients with abscesses to receive either a combination of Fentanyl IM followed by subcutaneous (SC) local bupivicaine analgesia or Normal Saline IM followed by SC local bupivicaine analgesia. Only opiate naive patients will be enrolled. The primary outcomes studied are patients overall satisfaction with procedure, and patients level of pain associated with the procedure.

NCT ID: NCT01853267 Completed - Perianal Abscess Clinical Trials

Perianal Abscess Packing Randomized ControlledTrial Pilot Study

Start date: May 2011
Phase: N/A
Study type: Interventional

TITLE Perianal Abscess Packing (PAP): a randomised controlled trial (Pilot study) DESIGN Randomised controlled trial. HYPOTHESIS In patients with perianal abscesses incision and drainage without packing the subsequent cavity will reduce patient discomfort without increasing healing time or recurrence compared with management involving cavity packing. OUTCOME MEASURES - Length of hospital stay - Time to cavity healing - Recurrent abscess or fistula formation - Pain score - Analgesia usage POPULATION All patients older than 18 years presenting with a perianal abscess. ELIGIBILITY Exclusion criteria: - under 18 years - those unable to give informed consent - abscesses associated with Crohn's disease or other underlying causes - abscesses in which initial drainage is considered inadequate (if the skin is not open sufficiently to allow drainage of the abscess cavity) DURATION Until recruitment of subjects is complete

NCT ID: NCT01814371 Completed - Clinical trials for Staphylococcus Aureus

Individualized vs. Household MRSA Decolonization

HOME2DS
Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of this research study is to compare the effectiveness of commonly used decolonization treatments (application of mupirocin antibiotic ointment to the nose and bleach baths) when performed by individuals with a history of skin and soft tissue infection (SSTI) in the prior year (individualized approach) in comparison to decolonization of all household members (household approach) in an attempt to prevent Staphylococcus aureus skin infections. The investigators hypothesize an individualized decolonization approach will be equally as effective as a household approach to prevent SSTI.

NCT ID: NCT01784458 Completed - Pneumonia Clinical Trials

Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe Sepsis

Start date: March 2009
Phase: N/A
Study type: Observational [Patient Registry]

- Intra-abdominal pressure(IAP) is defined as a steady state pressure of the abdominal cavity - many studies have proved IAP as a prognostic factor that elevated IAP influences hemodynamics and multiple organs dysfunction - In previous studies, most of them was based on the septic patients of medical diseases. And it is rare about sepsis of surgical diseases such as traumatized or postoperative patients - We hypothesized that intra-abdominal hypertension may affect clinical course such as length of stay of intensive care unit, weaning of mechanical ventilation, proceeding of enteral feeding and mortality - Our study was aimed to investigate prevalence of IAH and risk factors and to analyze clinical course and prognosis influenced by IAH in surgical patients with severe sepsis