Ectopic Pregnancy Clinical Trial
Official title:
The Comparison of Reproductive Outcomes of Hsyteroscopic Metroplasty Versus Spontaneous Coitus Plus COH/IUI Cycles in Unexplained Infertile Women With Dysmorphic Uterus
The correlation between dysmorphic uterus and infertility still remains enigmatic. We aim to evaluate the reproductive outcomes of metroplasty via office hysteroscopy in unexplained infertile women with dysmorphic uterus with comparing a group of unexplained infertile women performing 6 months spontaneous cycles plus 3 cycles controlled ovarian hyperstimulation and intrauterine insemination by randomized trial.
A dysmorphic uterus is a second-class (Class U1) uterine anomaly in the The European Society
of Human Reproduction and Embryology (ESHRE) and the European Society for Gynaecological
Endoscopy (ESGE) (ESHRE/ESGE) consensus on the classification of congenital genital tract
anomalies, which was formerly known as "T-shaped uterus" in the American Fertility Society
(AFS) Classification of Anomalies of the Müllerian Duct that leads to poor reproductive and
obstetric outcomes.
The reproductive performance of dysmorphic uterus is not well-known issue. We designed a
randomized trial in unexplained infertile couples women with dysmorphic uterus. After
allocation of properly selected women, hysteroscopy group will be undertaken metroplasty
procedure and 9 months follow-up period with natural conception. Second group will be
undertaken to six months spontaneous coitus and three cycles clomiphene citrate and
intrauterine insemination cycles. After nine months of follow-up of both groups, the
pregnancy and reproductive outcomes will be evaluated.
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