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Abortion clinical trials

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NCT ID: NCT06178224 Completed - Pregnancy Related Clinical Trials

Determining Beta-hCG Levels in Patients Through Alternative Sample Types

Start date: October 11, 2022
Phase:
Study type: Observational

This study is to determine if there is any quantifiable correlation between serum beta hCG and dried blood spot (DBS) beta hCG levels. This data will be used to develop a less invasive collection method to determine quantitative hCG levels.

NCT ID: NCT05839899 Recruiting - Abortion Clinical Trials

Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location

Start date: August 30, 2023
Phase: Phase 3
Study type: Interventional

Patients who seek medication abortion early in pregnancy may have an ultrasound that does not show a pregnancy in the uterus. This is known as a "pregnancy of unknown location". These patients most likely have a pregnancy in the uterus that is too early to be seen on ultrasound, but it is possible that the pregnancy is not seen inside the uterus because it is outside of the uterus, known as an ectopic pregnancy. Patients with ectopic pregnancies are at risk for serious complications, and the medications used for medication abortion may not end an ectopic pregnancy. Currently, at Planned Parenthood League of Massachusetts (PPLM), patients seeking medication abortion, including some patients with a pregnancy of unknown location, are given mifepristone to begin the medication abortion at the clinic and then one dose of misoprostol to take at home to cause the pregnancy to pass. However, research suggests that a second dose of misoprostol leads to a higher rate of completed abortion for certain patients. This research is being conducted to learn if two doses of the at-home misoprostol during the medication abortion process leads to a higher rate of completed abortion for patients with pregnancy of unknown location. In this study, all participants will receive mifepristone as they normally would. Then, participants will be randomly assigned to receive either one dose of misoprostol or two doses of misoprostol.

NCT ID: NCT05688228 Recruiting - Abortion Clinical Trials

Voluntary Interruption of Pregnancy on Women's Sexuality

VTOPSimpact
Start date: February 27, 2023
Phase:
Study type: Observational

The impact on sexuality has been less studied and there is no French study on this subject and the rare studies are contradictory. The aim of this study is to evaluate the impact of abortion (medical or surgical) on female sexuality, to look for a difference in the impact on sexuality according to the method used for the termination (medical or surgical) just after the procedure and at 1, 3 and 6 months and to look for risk factors and protective factors for the existence or occurrence of sexual dysfunction before and after abortion.

NCT ID: NCT05645614 Recruiting - Abortion Clinical Trials

Anxiety and Pain During Intervention for Abortion Under Local Anesthesia

ADIAL
Start date: December 9, 2022
Phase:
Study type: Observational

The aim of the study is to retrospectively analyze pain and anxiety assessment data previously collected in routine care in women who had an abortion under local anesthesia in order to identify the predictive factors of pain and anxiety, as well as to compare the results with previously published data. The participants are women who underwent abortion under local anesthesia in the gynecology department of the Pitié Salpêtrière Hospital between May and October 2021.

NCT ID: NCT05481606 Not yet recruiting - Hysterectomy Clinical Trials

Cesarean Scar Pregnancy and Clinical Outcomes

Start date: August 1, 2022
Phase:
Study type: Observational [Patient Registry]

This study is a prospective cohort study, led by Prof. Zhao Yangyu, from the Department of Gynecology & Obstetrics, Peking University Third Hospital.

NCT ID: NCT05471895 Not yet recruiting - Sexual Violence Clinical Trials

Impact of Sexual Violence on the Incidence of Voluntary Termination of Pregnancy in La Réunion

IVIIRun
Start date: January 2023
Phase:
Study type: Observational

According to the figures for the last three years collected from the Indian Ocean Regional Health Observatory, it appears to be about twice as many voluntary terminations of pregnancy on the island of Reunion compared with France metropolitain region. Furthermore, the overseas section in 2002, which looked at violence against women of all types in three different spheres of life (the marital sphere, the workplace and public spaces), tends to show a much higher incidence of sexual violence than in metropolitain France. This trend seems to be confirmed by the overseas section of the VIRAGE survey started in 2018 on the island. Furthermore, data found in a qualitative study conducted in Ile de France in 2013 seems to demonstrate a more frequent use of abortion among patients who are victims of sexual violence. Thus, thiçs study will consist in evaluating the impact of sexual violence on the incidence of voluntary termination of pregnancy in Reunion Island.

NCT ID: NCT04651166 Completed - Hemorrhage Clinical Trials

Effect of Prophylactic Tranexamic Acid on Bleeding Outcomes for Dilation and Evacuation

Start date: February 15, 2022
Phase: Phase 2
Study type: Interventional

Prophylactic tranexamic acid has shown been shown to reduce maternal mortality from postpartum hemorrhage with no adverse effects, but has not been studied to reduce bleeding complications with dilation and evacuation (D&E). We propose a randomized, double-blinded, placebo-controlled pilot study to determine whether routine use of intravenous (IV) tranexamic acid will decrease the need for interventions to control bleeding at the time of D&E at 16 to 24 weeks gestation.

NCT ID: NCT04181021 Completed - Contraception Clinical Trials

Evaluation of Values Clarification and Attitude Transformation Workshops on Abortion and Family Planning Service Provision and Client Experience

Start date: November 25, 2019
Phase: N/A
Study type: Interventional

Stigma around abortion and other reproductive health care is pervasive in most contexts and has been documented to have implications for the quality of care. This study aims to assess how Values Clarification and Attitude Transformation (VCAT) workshops for providers of abortion and family planning services influences service provision of abortion and family planning services, including the quality and person-centeredness of care provided. A secondary aim is to measure how provider attitudes, knowledge, and behavioral intent change over time as a result of the VCAT workshop.This study will be conducted across multiple regions in Ethiopia.

NCT ID: NCT03688581 Recruiting - Abortion Clinical Trials

What is the Knowledge and Use of Emergency Contraception

Start date: July 1, 2018
Phase:
Study type: Observational

The main objective is to assess the knowledge of women seeking abortion about emergency contraception. The secondary objectives are to evaluate the use of emergency contraception among women seeking abortion and to identify barriers to the efficacy and use of emergency contraception in these women.

NCT ID: NCT03579550 Enrolling by invitation - Ectopic Pregnancy Clinical Trials

Hysteroscopic Metroplasty in Unexplained Infertile Women With Dysmorphic Uterus

COH/IUI
Start date: June 8, 2018
Phase: N/A
Study type: Interventional

The correlation between dysmorphic uterus and infertility still remains enigmatic. We aim to evaluate the reproductive outcomes of metroplasty via office hysteroscopy in unexplained infertile women with dysmorphic uterus with comparing a group of unexplained infertile women performing 6 months spontaneous cycles plus 3 cycles controlled ovarian hyperstimulation and intrauterine insemination by randomized trial.