Abortion in First Trimester Clinical Trial
Official title:
Pharmacist Provision of Medication Abortion Pilot
This will be a pilot study among two pharmacists providing start to finish medication abortions to 10 patients utilizing a previously created toolkit. Following completion of the pilot, we will perform in-depth semi-structured interviews with the participating patients and pharmacists to understand their experiences with pharmacist provision of medication abortion. In addition, we will elicit feedback about ways to refine the toolkit to support the scale-up of pharmacist provision of medication abortion in the future.
Status | Recruiting |
Enrollment | 10 |
Est. completion date | September 1, 2022 |
Est. primary completion date | July 1, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 50 Years |
Eligibility | Inclusion Criteria: - Age 18 or older - Pregnancy must be confirmed by either patient report of a positive urine pregnancy test, serum pregnancy test or ultrasound - Patient's last menstrual period (LMP) must be less than 70 days before the anticipated date of mifepristone administration - Patient must be certain of their LMP within 7 days and have regular menses - Patient has no symptoms or risk factors for ectopic pregnancy including bleeding or spotting in the week before their visit, prior ectopic pregnancy, significant pelvic pain the last week, prior permanent contraception or tubal surgery, current intrauterine device (IUD) in place or IUD in place at time of conception. Exclusion Criteria: - Any contraindications to medication abortion, as reported on their medical history. These contraindicated include: 1. Hemorrhagic bleeding disorder 2. Current anticoagulation therapy 3. Chronic adrenal failure 4. Long-term systemic corticosteroid therapy 5. Inherited porphyria d) Allergy to misoprostol or mifepristone - Any patient with complex medical conditions will also be excluded from this initial pilot. These medical conditions include: 1. Poorly controlled hypertension as defined a history of systolic blood pressure >160 or diastolic blood pressure >110 or patients requiring two or more antihypertensive medication to control their blood pressure. This will be exclusion criteria for the study but it not a standard exclusion criteria for medication abortion 2. Poorly controlled diabetes as defined by a known history of Type 1 or Type 2 diabetes with history of finger stick blood sugar >200 or HbA1c>10 in the last 6 months. This will be exclusion criteria for the study but it not a standard exclusion criteria for medication abortion 3. Hepatic or renal failure 4. History of solid organ transplant 5. 4 or more cesarean sections 6. Allergy to NSAIDs. |
Country | Name | City | State |
---|---|---|---|
United States | University of California, San Diego | La Jolla | California |
Lead Sponsor | Collaborator |
---|---|
University of California, San Diego |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Completion of Medication Abortion | Negative Pregnancy Test | 6 weeks | |
Secondary | Patient Satisfaction | qualitative analysis of post abortion in depth interviews | 2 weeks following completion of medication abortion | |
Secondary | Pharmacist Experience | qualitative analysis of post pilot in depth interviews | 2 weeks following completion of all 10 medication abortion visits | |
Secondary | Toolkit changes | per recommendation by participating pharmacists at post pilot in depth interviews | 2 weeks following completion of all 10 medication abortion visits |
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