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Abdominal Injuries clinical trials

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NCT ID: NCT06339073 Completed - Wounds and Injuries Clinical Trials

CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma

Start date: October 1, 2023
Phase:
Study type: Observational

Critically ill patients often require tracheal intubation for mechanical ventilation, and timely weaning is crucial for airway management and reducing complications. However, there is currently a lack of an effective tool to predict weaning time in critically ill patients. This retrospective study established an effective nomogram model for predicting the time of weaning from mechanical ventilation in abdominal trauma patients by considering multiple perspectives. The model has been validated and demonstrated good performance in terms of discrimination, calibration, and clinical utility. Moreover, the model can effectively predict the prognosis of critically ill patients. The findings of this study have important implications for guiding respiratory management in clinically critically ill patients, particularly trauma patients.

NCT ID: NCT06228261 Not yet recruiting - Clinical trials for Penetrating Abdominal Trauma

Critical Analysis of the Results in the Management of Penetrating Abdominal Trauma in the Past Fifteen Years.

PAT-HMAR
Start date: March 15, 2024
Phase:
Study type: Observational

Penetrating abdominal trauma (PAT) incidence varies between 3,1-12,8% and it comprises a wide range of injuries with varying patterns on diagnostic imaging. Last guidelines published in 2014 recommend the use of FAST and CXR as the Gold Standard method for evaluating. Computed Tomography (CT) is widely used in stable patients with PAT and it requires intravenous contrast and patient irradiation, leading to additional costs to healthcare services. This study aims to assess the management of PAT in our institution and with its results review the actual protocol.

NCT ID: NCT06182488 Recruiting - Acute Abdomen Clinical Trials

Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Emergency Laparotomy

ERAS
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the safety and effectiveness of the ERAS protocols compared to a conventional care protocols in patients who received emergency laparotomy. The main question it aims to answer are: • Can the ERAS protocols be used safely and effectively in patients undergoing emergency laparotomy? Participants will be randomised into the ERAS group and the conventional group and will be given the ERAS protocols and the conventional protocols in the perioperative period. Researchers will compare the ERAS group with the conventional group to see if the ERAS programme is effective.

NCT ID: NCT06180668 Not yet recruiting - Abdominal Trauma Clinical Trials

Global Outcomes After Laparotomy for Trauma

GOAL-Trauma
Start date: April 2024
Phase:
Study type: Observational

The goal of this observational study is to assessing the global variation in patient characteristics, management, and outcomes in those undergoing trauma laparotomy. The main questions it aims to answer are: - What are the post-operative mortality rates for patients undergoing a trauma laparotomy globally - What are the epidemiological characteristics (demographics, injury characteristics, baseline clinical characteristics, and surgical case mix) for patients undergoing a trauma laparotomy - What are the pre-operative, peri-operative, and post-operative processes of care for patients undergoing a trauma laparotomy This is a purely observational study on patients undergoing trauma laparotomy, with no direct change to clinical care.

NCT ID: NCT06065202 Recruiting - Abdominal Trauma Clinical Trials

Personalized Nutrition to Improve Recovery in Trauma

SeND Home
Start date: April 12, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if a particular method of providing nutrition improves the outcomes of patients in the intensive care unit (ICU) who have undergone abdominal surgery following trauma and would require nutrition delivered via the bloodstream (called total parenteral nutrition or TPN). The nutrition method being tested is a structured nutrition delivery plan, called the SeND Home pathway, that involves TPN, oral nutrition supplements, and the use of a device (called an indirect calorimeter or IC) to measure calorie needs. Participants will be randomly assigned (like the flip of a coin) to the SeND Home program or standard of care nutrition. In the SeND Home program, participants will receive TPN, followed by oral nutrition supplements (shakes) for 4 weeks after discharge. The control group will follow standard of care nutrition delivery that begins during ICU stay and concludes at hospital discharge. Participants in both groups will undergo non-invasive tests that measure how much energy (calories) they are using, body composition, and muscle mass and complete walking and strength tests, and surveys about quality of life.

NCT ID: NCT06043414 Not yet recruiting - Laparotomy Clinical Trials

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory laparotomy. The study addresses the common complications of incisional surgical site infections (SSI) and fascial dehiscence (FD) following emergency exploratory laparotomy. The primary objective is to assess the effectiveness of triclosan-coated barbed suture and conventional non-barbed suture in reducing the rates of incisional SSI and FD within 30 days postoperatively. The study population comprises adult patients undergoing emergent laparotomy for traumatic injuries or acute intraabdominal pathology. This prospective, single-blinded randomized control trial will be conducted at Los Angeles General Medical Center. Patients will be randomized to receive either triclosan-coated barbed suture or conventional non-barbed suture for abdominal fascial closure, with a standard closure technique employed. Patients will be followed up for 30 days postoperatively to monitor surgical site infections, fascial dehiscence, and other outcomes. Statistical analysis will be conducted to compare outcomes between the study arms, assessing the efficacy of triclosan-coated barbed suture in reducing the incidence of SSI and FD, along with secondary outcomes.

NCT ID: NCT05910567 Recruiting - Wounds and Injuries Clinical Trials

A Research Study of Abdominal Ultrasound (FAST) in Children With Blunt Torso Trauma

FAST
Start date: April 17, 2023
Phase: N/A
Study type: Interventional

Bleeding from intra-abdominal injuries is a leading cause of traumatic deaths in children. Abdominal CT is the reference standard test for diagnosing intra-abdominal injuries. Compelling reasons exist, however, to both aggressively evaluate injured children for intra-abdominal injuries with CT and to limit abdominal CT evaluation to solely those at non-negligible risk. The focused assessment sonography for trauma (FAST) examination can help focus patient evaluation in just this manner by potentially safely decreasing abdominal CT use in low risk children. This research study is a multicenter, randomized, controlled trial to determine whether use of the FAST examination, a bedside abdominal ultrasound, impacts care in 3,194 hemodynamically stable children with blunt abdominal trauma. The overall objectives of this proposal are 1) to determine the efficacy of using the FAST examination during the initial evaluation of children with blunt abdominal trauma, and 2) to identify factors associated with abdominal CT use in children considered very low risk for IAI after a negative FAST examination. The long-term objective of the research is to determine appropriate evaluation strategies to optimize the care of injured children, leading to improved quality of care and a reduction in morbidity and mortality.

NCT ID: NCT05805852 Enrolling by invitation - Abdominal Trauma Clinical Trials

Challenges in Management of Abdominal Trauma in Sohag University Hospital A Prospective Study

Start date: March 1, 2023
Phase:
Study type: Observational

The present study will be conducted to evaluate the different patterns of abdominal trauma patients and their management in the Emergency Department of Sohag University Hospital

NCT ID: NCT05627908 Recruiting - Abdominal Trauma Clinical Trials

The PseAn Study - Study Protocol

PseAn
Start date: October 1, 2022
Phase:
Study type: Observational

The researchers aim to study the role of contrast ultrasound in detecting post-traumatic splenic, hepatic, and renal PAs compared with the gold standard of CT with intravenous contrast at different follow-up time points, and whether it can replace CT scan in the follow-up of solid organ injuries

NCT ID: NCT05538390 Completed - Abdominal Trauma Clinical Trials

Assessment of Pattern of Abdominal Injury

Start date: September 1, 2019
Phase:
Study type: Observational [Patient Registry]

This hospital-based cross-sectional study was done at SPHMMC and AaBET hospitals from January 2018 to December 2019.The study aimed to assess the pattern of abdominal injury at St Paul's Hospital Millennium Medical College (SPHMMC) and Addis Ababa Burn, Emergency and Trauma (AaBET) hospital, Addis Ababa Ethiopia.Data was collected from the trauma registry and patient files using a pretested structured questionnaire filled out by two trained data collectors.The collected data was entered and analyzed using statistical software SPSS version 25.0.