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Abdominal Injuries clinical trials

View clinical trials related to Abdominal Injuries.

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NCT ID: NCT03147690 Not yet recruiting - Abdominal Injury Clinical Trials

Contrast-Enhanced Ultrasound in the Evaluation of Abdominal Injuries in Children

Start date: June 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This study proposes to evaluate the accuracy of contrast-enhanced ultrasound (CEUS) in diagnosing abdominal solid organ injuries in pediatric patients. 146 subjects will be enrolled across approximately 8 sites in the US. All subjects will have had a Computerized Tomography (CT) scan as part of standard of care, confirming at least one solid organ abdominal injury. All subjects will have an abdominal ultrasound without contrast, followed by a contrast-enhanced ultrasound using the contrast agent Lumason. Ultrasound and contrast-enhanced ultrasound results will be compared to the CT scan results. The study procedures will take place within 48 hours of injury.

NCT ID: NCT03137732 Not yet recruiting - Pain, Postoperative Clinical Trials

Surgical Versus Anaesthetic Placement of Rectus Sheath Catheters

SPARC
Start date: June 2017
Phase: N/A
Study type: Interventional

This is a single centred randomized controlled trial comparing surgeon versus anaesthetist inserted rectus sheath catheters for management of analgesia post major abdominal surgery.

NCT ID: NCT03109483 Recruiting - Stroke Clinical Trials

Effectiveness of the Geriatric Activation Program Pellenberg (GAPP) on the Geriatric Rehabilitation Ward

Start date: March 17, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness of our developed week-treatment program GAPP, on strength, balance, speed, functionality and cognition, with the main goal to achieve a better independence for activities of daily living (ADL). Each day of the week an exercise program of 45 minutes is given assigned to a specific aspect of the rehabilitation; strength, balance, speed, functional training and one day is for testing or group therapy. Participants will be followed for four weeks, with testing on day one, after two weeks and at the last day of the four-week program.

NCT ID: NCT02952976 Not yet recruiting - Clinical trials for Abdominal Compartment Syndrome

Study of Primary Fascial Closure Rate in Patients With Open Abdomen Treated With Abthera Versus Barker Technique

Start date: July 1, 2017
Phase: Phase 3
Study type: Interventional

This study is being done to compare two different Temporary Abdominal Closure methods that could be used in cases like yours. The methods being compared are the Barker's vacuum packing technique (BVPT) and the Open Abdomen Negative Pressure Therapy System (ABThera).

NCT ID: NCT02831556 Recruiting - Pregnancy Clinical Trials

Point of Care 3D Ultrasound for Various Applications: A Pilot Study

Start date: July 2016
Phase: N/A
Study type: Observational

Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images. The study will use a newly developed acquisition method and post-processing technique to create three dimensional image models of the abdomen and/or pelvis. 2. Study activities and population group. The study population will be a convenience sample of patients of any age presenting to the Emergency Department with complaints necessitating a clinical abdominal and/or pelvic imaging. The study intervention includes acquisition of research ultrasound images, which will not be used for clinical care, and comparison of these images with clinically obtained images. Other clinical data such as surgical and pathology reports will also be reviewed. 3.Data analysis and risk/safety issues. This is a pilot study intended to determine feasibility and to refine image reconstruction algorithms. Research images will be compared to clinical images. Comparison of research images with final diagnosis will also occur. The research intervention, an ultrasound exam, has no known safety risks. The only risk to subjects is loss of confidentiality. This study is observational, not interventional, because the experimental ultrasound will be performed in all subjects and will not be used in the clinical care of patients (consequently, will not have the opportunity to affect clinical outcomes). Experimental images will be reviewed after completion of clinical care and will not be provided to the clinicians caring for the subjects. The investigators are not measuring the effect of the ultrasound examination on the subjects' outcomes.

NCT ID: NCT02829125 Recruiting - Abdominal Injuries Clinical Trials

Influence of Postoperative Rehabilitation and Pre- and Postoperative Physical Activity in Abdominal Surgery

Start date: January 1, 2015
Phase: N/A
Study type: Observational

The concept of early rehabilitation (ERAS: enhanced after-surgery recovery) was introduced by Kehlet et al. in 1995, as part of the colon surgery. This program is a support for patients combining laparoscopic surgery, epidural analgesia, early refeeding and rapid mobilization of patients. This strategy targets multiple elements (20 items) to support pre-, intra- and postoperative patients. This reduces the pain and the different organ dysfunction induced by surgical stress significantly decreasing length of hospital stay, postoperative morbidity and costs. Furthermore, early mobilization of patients is fundamental to the ERAS method. Few studies have analyzed the influence of preoperative exercise on postoperative rehabilitation.

NCT ID: NCT02728609 Completed - Abdominal Trauma Clinical Trials

An Analysis of Cytokine Concentration in Open Abdominal Closure of Trauma Patients

Start date: March 2010
Phase: N/A
Study type: Observational

The purpose of this study is to compare the pro-inflammatory and anti-inflammatory cytokines, protein content, and white blood cell (WBC) count present in the peritoneal fluid and plasma of trauma patients who undergo one of two different methods of open abdominal closure. Following analysis of the peritoneal fluid and serum samples, comparison of the results between the two groups will be completed and correlated with the overall organ function.

NCT ID: NCT02542241 Recruiting - Abdominal Injuries Clinical Trials

Hypertonic Saline Resuscitation in Trauma Patients After Hemorrhage Control

CELTA
Start date: December 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether hypertonic saline solution is effective in the resuscitation of traumatized patients undergone abdominal damage control surgery regarding early closure of the abdominal wall.

NCT ID: NCT02206698 Recruiting - Clinical trials for Pediatric Abdominal Trauma

Pediatric Blunt Abdominal Trauma Clinical Prediction Model

Start date: July 2014
Phase: N/A
Study type: Observational [Patient Registry]

The submitted proposal is designed to reduce morbidity and mortality to injured children. Significant variability in the initial trauma assessment exists among institutions. The proposed project is a prospective, observational, multi-institutional study of children following blunt abdominal trauma. The specific goals of the project are to: 1) Document history, physical exam findings, imaging, and laboratory values, which are available to physicians during the initial trauma resuscitation prior to a decision on whether to order an abdominal computed tomography (CT) to evaluate for potential intra-abdominal injury; and 2) Derive and validate a multi-variable clinical prediction rule based on data variables readily available during the pediatric trauma resuscitation to identify patients at low risk for intra-abdominal injury, in which unnecessary CT might safely be avoided. Information from this study could be used to develop a more standardized approach to the evaluation for intra-abdominal injury following blunt trauma in children. This information could lead to significant improvement in the early recognition of injury and to improved resource utilization.

NCT ID: NCT01971892 Active, not recruiting - Surgery Clinical Trials

Non Invasive Ventilation in Abdominal Postoperative Period

NIVAS
Start date: May 2013
Phase: N/A
Study type: Interventional

Acute respiratory failure may occur early in the postoperative course, requiring endotracheal intubation and mechanical ventilation in selected patients, thus increasing morbidity and mortality and prolonging intensive care unit (ICU) and hospital stay.We will perform a multicenter, prospective, randomized clinical trial to compare the efficacy of non invasive ventilation (NIV) which associated pressure support ventilation (PSV: 5 to 15 cmH2O) and positive end expiratory pressure (PEEP: 5 to 10 cmH2O) with standard oxygen therapy in the treatment of postoperative acute respiratory failure. We also set out to examine the hypothesis that early application of NIV may prevent intubation and mechanical ventilation in patients who develop acute respiratory failure after abdominal surgery.