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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT02362022
Other study ID # 14.09.2007/88-4
Secondary ID
Status Completed
Phase Phase 4
First received February 4, 2015
Last updated December 2, 2015
Start date September 2007
Est. completion date December 2007

Study information

Verified date June 2015
Source Baskent University
Contact n/a
Is FDA regulated No
Health authority Unspecified
Study type Interventional

Clinical Trial Summary

Combination of volatile and opioid agents are used to achieve unconsciousness, haemodynamic stability and analgesia for surgical prosedures. This prospective, randomized, double-blind, controlled study evaluates the effects of two different doses of morphine sulphate (0.1 mg/kg and 0.2 mg/kg), on desflurane consumption, recovery characteristics, postoperative analgesic requirements and side effects during total abdominal hysterectomy.


Recruitment information / eligibility

Status Completed
Enrollment 90
Est. completion date December 2007
Est. primary completion date December 2007
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 40 Years to 60 Years
Eligibility Inclusion Criteria:

- undergoing total abdominal hysterectomy with general anaesthesia

Exclusion Criteria:

- renal dysfunction (cre>1.2), liver failure, cardiovascular, psychiatric, allergic and metabolic disorders

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Caregiver, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


Intervention

Drug:
Morphine
Group Saline (Group S): Received i.v saline 0.9 % in 10 ml volume (n=30) Group Morphine 1 (Group M1): Received i.v morphine 0.1 mg kg-1 in 10 ml volume (n=30) Group Morphine 2 (Group M2): Received i.v morphine 0.2 mg kg-1 in 10 ml volume (n=30)

Locations

Country Name City State
Turkey Baskent University School of Medicine Adana Teaching and Research Hospital Adana

Sponsors (1)

Lead Sponsor Collaborator
Baskent University

Country where clinical trial is conducted

Turkey, 

Outcome

Type Measure Description Time frame Safety issue
Primary postoperative desflurane consumption postoperative first hour Yes
Primary sedation scores for OASS scale postoperative first hour Yes
See also
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Completed NCT03064308 - The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery N/A
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