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Abdominal Hysterectomy (& Wertheim) clinical trials

View clinical trials related to Abdominal Hysterectomy (& Wertheim).

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NCT ID: NCT05644873 Recruiting - General Anesthesia Clinical Trials

Intravenous Administration of Magnesium Sulfate in Hysterectomy Cases

Start date: November 15, 2023
Phase: N/A
Study type: Interventional

In our study, it was aimed to show the contribution of intraoperative intravenous magnesium sulfate administration to peroperative opioid consumption and postoperative analgesia.

NCT ID: NCT05611944 Completed - Clinical trials for Surgical Site Infection

Irrigation and Suction Trial to Prevent SSI

I&S
Start date: April 1, 2017
Phase: N/A
Study type: Interventional

The study will be conducted on women with risk factors for SSI assigned to gynecological surgery with an open abdominal approach. The participants will be designated to either Irrigation and suction arm by bilateral drain insertion or the control arm by randomization through the parallel assignment. The participants will be followed for the outcome for four days in the hospital and then at 4 weeks, 8 weeks and 12 weeks postoperatively. The primary outcome measure will be the SSI rate. Secondary outcomes will be signs of SSI, post-operative pain, other complications and patient satisfaction.

NCT ID: NCT05420662 Completed - Clinical trials for Abdominal Hysterectomy

The Application of Vaginal Manipulator in Abdominal Hysterectomy Operations

Start date: July 14, 2022
Phase: N/A
Study type: Interventional

If a vaginal manipulator is used for abdominal hysterectomy, the vagina can be cut and separated from the cervix without cutting the Cardinal and Sacrouterine ligaments and protecting the top of the vaginal tissue (Portio vaginalis). In this way, both the shortening of the vagina and the prolapse of the vaginal cuff can be prevented. In addition, the duration of hysterectomy surgery is significantly shortened.

NCT ID: NCT04724564 Completed - Clinical trials for Abdominal Hysterectomy

Correlation of Different Time Measurements of the Surgical PLETH Index With Postoperative Pain

Start date: February 1, 2021
Phase:
Study type: Observational

Despite the major progress in anesthetic techniques, postoperative pain is still considered a major problem during practice. (1-3). Leading to many co-morbidities, one to two-thirds of patients will suffer postoperative pain. These co-morbidities can include; pulmonary complications, cardiac complications, and delirium(4). Numerous risk factors are associated with the emergence of postoperative pain, including; younger age, female sex, preoperative pain, and extensive surgical procedure. The severity of postoperative pain may vary among patients undergoing the same operation (5-10). Many techniques have been evolved to monitor nociception and predict postoperative pain intensity; one of the most recent techniques is the surgical pleth index (SPI)(11).SPI is a noninvasive dimensionless score; its value is obtained from heartbeat interval and pulse wave amplitude monitored by pulse oximetry probe.SPI reflects the sympathetic response of the patient to the surgical stimuli(12-13). It was reported that SPI is better than other parameters like heart rate and blood pressure for detecting the balance between nociceptor activation and analgesia(14-15), and its value is correlated with the severity of postoperative pain. SPI values range from 0 to 100, and higher values indicate strong surgical stimulus (16). SPI can be used as a guide for intraoperative analgesia; hence, it can be a valuable tool to assess the analgesic requirement and limit opioid consumption, both preoperative and postoperative(17). Several studies have been performed to predict the severity of postoperative pain using SPI in adults and children (16,18). It was also used successfully to expect a hemodynamic response to tracheal intubation and skin incision (19) and monitor nerve block success. (20). However, since SPI has emerged, the most sensitive cut-off value that correlates well with postoperative pain severity remained debatable. Recent studies reported a value of 30 as a cut-off value of SPI. (21). On the other hand, the time of measurement to rely on was debatable. Most studies recommended that a measure of SPI before recovery can be used. However, a more recent study suggested that SPI response to surgical incision is highly correlated with postoperative pain and opioid consumption (18). Based on these data, we hypothesized that both measurements are correlated with postoperative pain and aimed to test which measure is more correlated.

NCT ID: NCT04366375 Completed - Clinical trials for Laparoscopic Hysterectomy

Pentraxin-3 in Hysterectomy Patients

Start date: January 13, 2015
Phase:
Study type: Observational

Comparison of the Tissue Trauma Markers Following Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy

NCT ID: NCT03965637 Completed - Clinical trials for Abdominal Hysterectomy

Intravenous Ascorbic Acid Administration in Hysterectomy

Start date: August 23, 2019
Phase: Phase 3
Study type: Interventional

vitamin C or ascorbic acid has known role in tissue repair. due to it's properties(water_soluble), vitamin c is not stored in the body and when depleted, the bleeding tendency will increase due to dysfunctional connective tissues production in vessel wall and it has some important functions in platelets.

NCT ID: NCT03748108 Completed - Clinical trials for Abdominal Hysterectomy

Bolus Administration of Intravenous Lidocaine at the Time of Abdominal Hysterectomy

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The objective of the study to evaluate whether a bolus administration of intravenous lidocaine decreases postoperative pain and represents an opioid-minimizing strategy after abdominal hysterectomy compared with placebo.

NCT ID: NCT03443271 Completed - Postoperative Pain Clinical Trials

Effect of TAP Block on Stress Hormones

Start date: June 17, 2016
Phase: Phase 4
Study type: Interventional

Random allocation of patients in two groups; Tap block group (T group) and control group (C group). All patients will receive standard general anesthesia and postoperative pain management. The TAP group patient will receive ultrasound guided (US) TAP block with 20 cc of 0.25% of bupivacaine and control group will receive 20cc of normal saline. TAP block in both groups will be performed with US guidance and the study drug will be injected after complete visualization of the needle tip between the internal oblique and the transversus abdominis muscles. Venous blood samples (5 ml for each time) for metabolic and stress hormones, including, Serum cortisol and nor-epinephrine will be collected before anesthesia at the time of cannulation (T1),60 minutes after incision(T2), 6hrs (T3)and 12 h (T4) after the surgery. Postoperatively patient will be put on patient controlled intravenous infusion of nalbuphine

NCT ID: NCT03064308 Completed - Quality of Life Clinical Trials

The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery

POETold
Start date: June 26, 2017
Phase: N/A
Study type: Interventional

The primary aim of this study is to establish if it is possible for patients who have undergone major body surgery to complete a home based exercise training program and complete the assessments required to measure physical and cognitive function. If the investigators can establish that it is feasible to complete the training and test's then further research can follow using these methods to determine whether it is possible to improve the physical function of older patients undergoing major abdominal surgery in the period following surgery by using a simple exercise regimen that can be carried out at home. By targeting physical function in this way the investigators hope to determine if it is a method for improving frailty and well being. In turn it may also have a positive impact on health service provision.

NCT ID: NCT02362022 Completed - Clinical trials for Abdominal Hysterectomy (& Wertheim)

The Effects of Morphine on Desflurane Consumption and Recovery Time

Start date: September 2007
Phase: Phase 4
Study type: Interventional

Combination of volatile and opioid agents are used to achieve unconsciousness, haemodynamic stability and analgesia for surgical prosedures. This prospective, randomized, double-blind, controlled study evaluates the effects of two different doses of morphine sulphate (0.1 mg/kg and 0.2 mg/kg), on desflurane consumption, recovery characteristics, postoperative analgesic requirements and side effects during total abdominal hysterectomy.