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Abdominal Cancer clinical trials

View clinical trials related to Abdominal Cancer.

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NCT ID: NCT02998736 Completed - Abdominal Cancer Clinical Trials

Trial of Perioperative Tadalafil and Influenza Vaccination in Cancer Patients Undergoing Major Surgical Resection of a Primary Abdominal Malignancy

PERIOP-04
Start date: November 21, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if giving Cialis for 5 days prior to surgery, on the day of surgery along with the influenza vaccine and Cialis 10 days after surgery will have an affect at the cell level for decreasing the chances of the spread of disease post surgery.

NCT ID: NCT02927379 Completed - Abdominal Cancer Clinical Trials

Effect of Wound Infiltration by Ketamine Versus Dexmedetomidine Added to Bupivacaine on Surgical Stress

Start date: June 2016
Phase: Phase 3
Study type: Interventional

This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on stress response and postoperative pain in lower abdominal cancer surgery.

NCT ID: NCT02912819 Completed - Abdominal Cancer Clinical Trials

Individualized Lung Recruitment Maneuver Guide by Pulse-oximetry in Anesthetized Patients

Start date: January 2016
Phase: N/A
Study type: Observational

General anesthesia and mechanical ventilation promotes atelectasis and airway closure. The open-lung approach (OLA) strategy restores the functional residual capacity. Pulse oximetry hemoglobin saturation (SpO2) using room air can diagnose shunt induced by lung collapse during general anesthesia and the SpO2 breathing air was useful to detect the lung´s opening and closing pressure during a recruitment maneuver (RM) in morbidly obese anesthetized patients. Investigators hypothesized that the SpO2 breathing air can personalize the open-lung approach.

NCT ID: NCT02566096 Completed - Abdominal Cancer Clinical Trials

Efficacy of Transverses Abdominis -Plane Block With Bupivacaine Versus Bupivacaine With Morphine Postoperatively

Start date: September 2015
Phase: Phase 4
Study type: Interventional

This study aims to compare the analgesic efficacy of transversus abdominis-plane block with bupivicaine versus bupivacaine with morphine in patients undergoing major abdominal cancer surgery.

NCT ID: NCT00780611 Completed - Abdominal Cancer Clinical Trials

Investigating the Improvement in 4D CT Images Using AV Biofeedback

GCC0832
Start date: November 2008
Phase:
Study type: Observational

This study will look at how tumors in the chest and abdomen move when you breathe. Your doctors are studying if extra 4D CT scans and instructions on how to breathe can help predict this type of movement and improve the accuracy of radiation treatment. 4D CT scans are approved by the FDA. A 4D CT scan is different from a regular CT because it moves slower and takes more pictures. It takes pictures of the way your body moves when you breathe. This gives doctors more pictures of your body so that they can match your pictures to the way you breathe. In this study, instructions on how to breathe will be visual and audio. Visual instructions will be given to you on a computer screen. You will hear audio instructions through a speaker.

NCT ID: NCT00494806 Completed - Abdominal Cancer Clinical Trials

Effects of Rocking on Postoperative Ileus Duration Study

Start date: July 2005
Phase: Phase 0
Study type: Interventional

Primary Objective: 1. Compare the duration of postoperative ileus (POI) duration (time to first flatus), subjective reports of surgical and gas pain, postoperative pain medication (total milligrams per 24 hours) and postoperative recovery time(length of stay) between two groups of abdominal surgery cancer patients receiving either standard postoperative care or standard care plus the rocking intervention.

NCT ID: NCT00415675 Completed - Lung Cancer Clinical Trials

Respiratory Tumor and Normal Tissue Motion

Start date: November 2004
Phase: N/A
Study type: Observational

Primary Objectives: - To collect accurate and reliable respiration-induced anatomic structure motion data using four-dimensional (4-D) imaging technology. - To analyze these data to study respiration-induced variations and patterns in variations of positions, shapes and volumes of tumors and normal anatomic structures in the thorax and abdomen over a breathing cycle, from one breathing cycle to the next, day-to-day and over the course of radiotherapy. - To assess dosimetric and potential clinical consequences of respiratory motion in the current practice of radiotherapy through preclinical treatment simulation (treatment planning) studies. - To quantify the potential consequences of explicitly accounting for respiration-induced motion on dose distributions and outcome (tumor control probabilities and normal tissue complication probabilities) through preclinical treatment simulation studies. Secondary Objectives: - To investigate the feasibility of using patient training to regulate patient breathing and improve the quality of images and to stratify patients for their eligibility for respiratory-correlated imaging and radiotherapy and for the implementation of various strategies for mitigation of respiratory-induced motion. - To assess the degree of correlation of the marker (or internal anatomic structure such as diaphragm) being tracked as surrogate of breathing with the motion of structures and the intra-fraction and inter-fraction reproducibility of such correlation. - To quantify the effects of radiation therapy on the patterns of respiratory-induced motion of structures through preclinical treatment simulation studies. - To compare various strategies for either accounting for or mitigating respiration-induced motion in the planning and delivery of radiation therapy.