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Abdominal Cancer clinical trials

View clinical trials related to Abdominal Cancer.

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NCT ID: NCT03460561 Completed - Abdominal Cancer Clinical Trials

Peri-operative Rectus Sheath Block Versus TEA Abdominal Surgeries

Start date: August 1, 2016
Phase: Phase 3
Study type: Interventional

Thoracic epidural analgesia (TEA) can be considered the gold standard for postoperative analgesia in major abdominal surgeries, as proved by a lot of number of systematic reviews and meta-analyses have demonstrated that TEA was associated with superior postoperative analgesia, better patients' outcomes, reducing (systemic opiate requirements, ileus and pulmonary complications). The rectus sheath block (RSB) is effective for the surgeries that necessitated midline abdominal incisions as local anesthetics instillation will be within the posterior rectus sheath bilaterally providing intense analgesia for the middle anterior wall from the xiphoid process to the symphysis pubis in adults.

NCT ID: NCT03459417 Enrolling by invitation - Abdominal Pain Clinical Trials

Safety and Efficacy of Intrathecally Administered Magnesium Sulfate

Start date: January 1, 2018
Phase: Phase 3
Study type: Interventional

Magnesium sulfate safety profile has been documented by histopathological analysis in experimental studies. magnesium sulfate added to local anesthetics decrease postoperative opioid requirements.

NCT ID: NCT03453424 Active, not recruiting - Abdominal Pain Clinical Trials

Analgesic Efficacy of Dexmedetomidine Added to Fentanyl in PCEA

Start date: June 30, 2017
Phase: Phase 3
Study type: Interventional

Dexmedetomidine if add to patient controlled epidural analgesia for patients undergoing major abdominal cancer surgery may improve its effects.

NCT ID: NCT03165383 Completed - Abdominal Cancer Clinical Trials

The Analgesic Efficacy of Ultrasound Guided Transversus Abdominal Plane Block After Abdominal Cancer Surgeries

TAP
Start date: February 11, 2013
Phase: N/A
Study type: Interventional

Effective postoperative pain control results in decreased cardiac and pulmonary complications, patient satisfaction and early mobilization. A prospective, randomized comparative study was done of analgesic efficacy, opioid requirement and side effects in patients undergoing lower abdominal cancer surgeries. In Study Group Ultrasound guided Transversus Abdominis Plane (TAP) block was given and control Group no TAP block was given. Patient controlled analgesia (PCA) with intravenous morphine was given to both group patients, and total good PCA demands in both the groups was studied.

NCT ID: NCT03144622 Recruiting - Breast Neoplasms Clinical Trials

18F-FSPG PET/CT Imaging in Patients With Cancers

Start date: September 6, 2016
Phase: N/A
Study type: Observational

This study aims to compare the diagnostic performance of 18F-FDG and 18F-FSPG PET/CT in lung, breast, and abdominal cancers before undergoing therapy. In addition, the role of 18F-FSPG PET/CT in evaluating therapy response and prognosis will also be evaluated.

NCT ID: NCT03120403 Completed - Abdominal Cancer Clinical Trials

Safety and Efficacy of Intrathecal Morphine in Children

Start date: July 1, 2016
Phase: Phase 2
Study type: Interventional

Postoperative pain in pediatrics can usually be well controlled with a combination of analgesics including acetaminophen ( paracetamol) ,NSIADS, opioids , and local/regional anesthesia.The use of epidural and subarachnoid morphine for analgesia in adults has grown almost as quickly as Morton`s discovery of anesthesia in 1846. The application of these techniques to the pediatric patients has evolved much more slowly,although significant progress is being made by many investigators.

NCT ID: NCT03102619 Completed - Clinical trials for Postoperative Complications

Wireless Assessment of Respiratory and Circulatory Distress; A Pilot Study

WARD
Start date: March 23, 2017
Phase: N/A
Study type: Observational

Postoperative observation of patients is based on the Early Warning Score (EWS). By using continuous wireless monitoring of vital parameters it may be possible to predict the risk of complications after abdominal cancer surgery. The object of this pilot study is to test the equipment and methods for the next phases. Patients will be monitored for 4 days postoperatively and data is analyzed retrospectively. Vital parameters are monitored with ECG, blood pressure monitor and pulseoximetry. In the analysis the investigators will compare the results from the continuous monitoring to the measurements made by the nurses and registered in the EWS. The primary outcomes for the pilot study are the frequency of measurements resulting in a single parameter score of 3 according to the EWS algorithm.

NCT ID: NCT03063112 Recruiting - Abdominal Cancer Clinical Trials

Radiofrequency and Chemical Neurolysis of Thoracic Splanchnic Nerve for Abdominal Cancer Pain

RF
Start date: October 1, 2016
Phase: N/A
Study type: Interventional

The study compares between the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation and chemical neurolysis of bilateral thoracic splanchnic nerves in the management of refractory pain which developed in patients suffering from upper abdominal cancer.

NCT ID: NCT02998736 Not yet recruiting - Abdominal Cancer Clinical Trials

Trial of Perioperative Tadalafil and Influenza Vaccination in Cancer Patients Undergoing Major Surgical Resection of a Primary Abdominal Malignancy

PERIOP-04
Start date: January 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if giving Cialis for 5 days prior to surgery, on the day of surgery along with the influenza vaccine and Cialis 10 days after surgery will have an affect at the cell level for decreasing the chances of the spread of disease post surgery.

NCT ID: NCT02927379 Completed - Abdominal Cancer Clinical Trials

Effect of Wound Infiltration by Ketamine Versus Dexmedetomidine Added to Bupivacaine on Surgical Stress

Start date: June 2016
Phase: Phase 3
Study type: Interventional

This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on stress response and postoperative pain in lower abdominal cancer surgery.