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Abdominal Abscess clinical trials

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NCT ID: NCT00931554 Completed - Pancreatic Fistula Clinical Trials

Randomized Trial of Early Versus Standard Drainage Removal After Pancreatic Resections

Start date: March 2007
Phase: N/A
Study type: Interventional

Despite a substantial decrease in postoperative mortality, morbidity after pancreatic resections is still high, even at high-volume centers. It has been recently suggested that early removal of postoperative drainages is associated to a decreased rate of intra-abdominal complications, with particular regard to pancreatic fistula. Furthermore, our research group demonstrated that measuring amylase value in drainages (AVD) on postoperative day 1 plays a cardinal role in predicting the developement of abdominal complications, including pancreatic fistula. In particular, patients with an AVD lower than 5000 IU/L in postoperative day 1 were considered at low risk of fistula. Therefore, the investigators designed a randomized prospective trial on early (postoperative day 3) versus standard (postoperative day 5) drainages removal after pancreatic resections in patients at low risk of developing pancreatic fistula (AVD < 5000 IU/L in postoperative day 1) to test whether drainages "per se" influence postoperative complication rates and to eventually validate a fast-track policy in pancreatic resections.

NCT ID: NCT00905502 Completed - Morbid Obesity Clinical Trials

Intraoperative Fluid Management in Laparoscopic Bariatric Surgery

Start date: April 2007
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the effects of 'high' versus 'low' volume intraoperative fluid administration (Ringer Lactate, RL) on intra- and postoperative parameters, in obese patients undergoing laparoscopic bariatric surgery (i.e., gastric bypass), in order to establish evidence-based data for perioperative fluid management in this patient population. Based on their experience as well as several reports in the literature, the investigators hypothesized that a restrictive approach to intraoperative hydration will reduce the incidence of postoperative complications and the recovery time of gastrointestinal (GI) function, and shorten hospital stay.

NCT ID: NCT00802854 Completed - Candidemia Clinical Trials

Post Marketing Surveillance Study To Observe Safety And Efficacy Of Eraxis® IV

Start date: March 2, 2012
Phase:
Study type: Observational

The objective of this study is to collect the safety and efficacy data of Eraxis IV (anidulafungin) 100 mg according to Korea Ministry of Food and Drug Safety regulations.

NCT ID: NCT00629135 Completed - Clinical trials for Abscess, Intra-Abdominal

Moxifloxacin Plus Metronidazole Versus Piperacillin/Tazobactam for the Treatment of Patients With Intra-abdominal Abscesses

MEMO
Start date: November 15, 2005
Phase: Phase 3
Study type: Interventional

The study is contemplating the antibiotic therapy of intraabdominal abscesses. These abscesses are a serious problem in surgical practice. Associated pathophysiologic effects as for example peritonitis may become life threatening or may lead to extended periods of morbidity with prolonged hospitalization. The objective of the sudy is to evaluate whether the combination of Moxifloxacin and Metronidazole is equivalent to Piperacillin / Tazobactam with regard to clinical outcome and eradication of aerobe and anaerobe pathogens in patients with intra-abdominal abscesses.

NCT ID: NCT00515034 Completed - Pneumonia Clinical Trials

A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumonia

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of doripenem compared to imipenem in Ventilator-assisted pneumonia and complicated Intra-abdominal Infection. The study population will include hospitalized patients (or patients resident in a chronic health care facility) who have a diagnosis of either Ventilator associated pneumonia or complicated Intra-abdominal Infection.

NCT ID: NCT00488306 Completed - Abdominal Abscess Clinical Trials

Study Evaluating the Safety and Efficacy of Tigecycline in Hospitalized Patients With cIAI

Start date: August 2006
Phase: Phase 4
Study type: Interventional

In light of tigecycline's activity against these resistant bacteria, tigecycline may represent a viable new therapy for complicated intra-abdominal infections.

NCT ID: NCT00284739 Completed - Abdominal Abscess Clinical Trials

Alteplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses

Start date: February 2006
Phase: Phase 2
Study type: Interventional

Intracavitary injection of low dose alteplase into loculated abdominopelvic abscesses will reduce the duration of percutaneous drainage and increase the proportion of successful drainages.

NCT ID: NCT00230971 Completed - Appendicitis Clinical Trials

Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)

Start date: October 2005
Phase: Phase 4
Study type: Interventional

This is a study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI. Subjects will be followed for efficacy through the test-of-cure assessment. Safety evaluations will occur through the treatment and post-treatment periods and continue through resolution or stability of the adverse event(s).

NCT ID: NCT00136201 Completed - Abdominal Abscess Clinical Trials

Study Comparing Tigecycline and Imipenem/Cilastatin in Chinese Subjects With Complicated Intra-Abdominal Infections

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to compare the safety and efficacy of an experimental antibiotic to a marketed antibiotic in the treatment of Chinese subjects with complicated intra-abdominal infections. <br />